Nasaruplase Gamma

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 19:16:20 GMT 2023` Edited by `admin` on `Sat Dec 16 19:16:20 GMT 2023`
Protein Type	PROPROTEIN
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	66522BCB6P
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Nasaruplase Gamma

Official Name

English

Pro-urokinase-type plasminogen activator (recombinant human LTI-01)

Common Name

English

nasaruplase gamma [INN]

Common Name

English

human urokinase-type plasminogen activator (U-plasminogen activator, uPA, PLAU, EC:3.4.21.73), single-chain pro-protein (pro-urokinase), produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, clone 8-93, glycoform gamma

Common Name

English

Code System Code Type Description

FDA UNII

66522BCB6P

Created by admin on Sat Dec 16 19:16:20 GMT 2023 , Edited by admin on Sat Dec 16 19:16:20 GMT 2023

PRIMARY

CAS

2647419-93-8

Created by admin on Sat Dec 16 19:16:20 GMT 2023 , Edited by admin on Sat Dec 16 19:16:20 GMT 2023

PRIMARY

NCI_THESAURUS

C187085

Created by admin on Sat Dec 16 19:16:20 GMT 2023 , Edited by admin on Sat Dec 16 19:16:20 GMT 2023

PRIMARY

INN

12267

Created by admin on Sat Dec 16 19:16:20 GMT 2023 , Edited by admin on Sat Dec 16 19:16:20 GMT 2023

PRIMARY

From	To
1_352	1_380
1_325	1_341
1_293	1_362
1_197	1_268
1_189	1_205
1_148	1_279
1_102	1_126
1_71	1_113
1_50	1_131
1_33	1_42
1_13	1_31
1_11	1_19

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_302
O	1_18

Related Record Type Details


					66522BCB6P

Nasaruplase Gamma

ACTIVE MOIETY

Comments:

limited intrinsic protease activity.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL