Timdarpacept

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:18:16 GMT 2025` Edited by `admin` on `Wed Apr 02 17:18:16 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	PHOSPHATASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	664WQ5KSP8
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

human signal-regulatory protein alpha (SIRP?, tyrosine-protein phosphatase non-receptor type substrate 1) receptor domain 1 fragment (1-133) natural variant V2 (SIRP? V2; L 14 >S, T20 >S, T 22 >I, R24 >H, A 27 >V, G 45 >A, D 65 >E, L 66 >S, N70 >E, R 77

Preferred Name

English

Timdarpacept

Official Name

English

timdarpacept [INN]

Common Name

English

Code System Code Type Description

SMS_ID

300000052740

Created by admin on Wed Apr 02 17:18:16 GMT 2025 , Edited by admin on Wed Apr 02 17:18:16 GMT 2025

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CAS

2749520-17-8

Created by admin on Wed Apr 02 17:18:16 GMT 2025 , Edited by admin on Wed Apr 02 17:18:16 GMT 2025

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FDA UNII

664WQ5KSP8

Created by admin on Wed Apr 02 17:18:16 GMT 2025 , Edited by admin on Wed Apr 02 17:18:16 GMT 2025

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INN

12555

Created by admin on Wed Apr 02 17:18:16 GMT 2025 , Edited by admin on Wed Apr 02 17:18:16 GMT 2025

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NCI_THESAURUS

C199120

Created by admin on Wed Apr 02 17:18:16 GMT 2025 , Edited by admin on Wed Apr 02 17:18:16 GMT 2025

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From	To
1_147	2_147
1_144	2_144
1_138	2_138
2_285	2_343
2_179	2_239
2_25	2_91
1_285	1_343
1_179	1_239
1_25	1_91

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
C	1_215
C	2_215

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_365] [2_365]	C-TERMINUS	K		LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL