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LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR
662XT84BPG
Other
General
Record Details
Names
12
Identifiers
2
Subunits
1
Disulfide Links
4
Glycosylation
1
Relationships
2
Modifications
1
Characteristic Attributes
2
LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR
662XT84BPG
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Record UNII
662XT84BPG
Record Status
Validated (UNII)
Record Version
6
5
4
3
2
1
Names
12
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5
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entries
Name
Type
Language
Name
Type
Language
CD-23
Preferred Name
English
LOW AFFINITY IMMUNOGLOBULIN EPSILON FC RECEPTOR
Common Name
English
LYMPHOCYTE IGE RECEPTOR
Common Name
English
IGEBF
Common Name
English
FCER2
Common Name
English
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Identifiers
2
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Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
662XT84BPG
PRIMARY
UNIPROT
P06734
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Disulfide Links
4
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entries
From
To
From
To
1_160
1_288
1_163
1_174
1_191
1_282
1_259
1_273
Showing 1 to 4 of 4 entries
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Glycosylation
1
Glycosylation Type
HUMAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_63
Showing 1 to 1 of 1 entries
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Relationships
2
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entries
Related Record
Type
Details
Related Record
Type
Details
8Z13S29R5A
GOMILIXIMAB
INHIBITOR -> TARGET
XK0D8BK5WY
MEDI-4212
INHIBITOR -> TARGET
Comments:
MEDI4212 is directed against IgE, effectively blocking Fc?RI and CD23, and thereby preventing an IgE-mediated response.
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Modifications
1
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO ACID SUBSTITUTION
[1_17] [1_18]
CYSTEINE
S-PALMITOYL CYSTEINE
08WQ73S7SV
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 36500 Da (average)
Molecular Formula
CHEMICAL
ESTIMATED
C1610H2521N464O503S17
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