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Details

Stereochemistry ACHIRAL
Molecular Formula 2K.O5S2
Molecular Weight 222.324
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of POTASSIUM METABISULFITE

SMILES

[K+].[K+].[O-]S(=O)S([O-])(=O)=O

InChI

InChIKey=RWPGFSMJFRPDDP-UHFFFAOYSA-L
InChI=1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

HIDE SMILES / InChI
Molecular Formula O5S2
Molecular Weight 144.127
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

METABISULFITE ION is a food additive, also known as E-224. It is used as the preservative in processed fruit products including dried fruits, juices, and wine.

Approval Year

1982
100
PubMed

PubMed

TitleDatePubMed
Effects of sodium metabisulfite on the expression of BK(Ca), K(ATP), and L-Ca(2+) channels in rat aortas in vivo and in vitro.
2015 Mar 2
Preservation of fruit and vegetable discards with sodium metabisulfite.
2018 Oct 15

Sample Use Guides

In Vitro Use Guide
The purpose of the study was to investigate the effect of sodium metabisulfite (SMB) on the expression of big-conductance Ca(2+)-activated K(+) (BKCa), ATP-sensitive K(+) (KATP), and L-type calcium (L-Ca(2+)) channels in rat aorta in vivo and in vitro. The results showed that the mRNA and protein levels of the BKCa channel subunits α and β1 of the aorta in rats were increased by SMB in vivo and in vitro. Similarly, the expression of the KATP channel subunits Kir6.1, Kir6.2, and SUR2B were increased by SMB. However, SMB at the highest concentration significantly decreased the expression of the L-Ca(2+) channel subunits Cav1.2 and Cav1.3.
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:56:56 UTC 2023
Edited
by admin
on Fri Dec 15 15:56:56 UTC 2023
Record UNII
65OE787Q7W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POTASSIUM METABISULFITE
EP   FCC   HSDB   II   INCI   MART.   MI   VANDF   WHO-DD  
INCI  
Official Name English
POTASSIUM METABISULFITE [EP IMPURITY]
Common Name English
SOBISU
Common Name English
POTASSIUM METABISULFITE [INCI]
Common Name English
POTASSIUM DISULFITE
Systematic Name English
Potassium metabisulfite [WHO-DD]
Common Name English
E-224
Common Name English
POTASSIUM METABISULFITE [EP MONOGRAPH]
Common Name English
POTASSIUM METABISULFITE [HSDB]
Common Name English
POTASSIUM METABISULFITE [II]
Common Name English
Dipotassium pyrosulfite
Systematic Name English
POTASSIUM METABISULFITE [FCC]
Common Name English
POTASSIUM METABISULFITE [MI]
Common Name English
POTASSIUM METABISULPHITE
Systematic Name English
POTASSIUM METABISULFITE [MART.]
Common Name English
POTASSIUM PYROSULFITE
Systematic Name English
POTASSIUM METABISULFITE (E 224)
Common Name English
FERTISILO
Common Name English
INS-224
Common Name English
POTASSIUM METABISULFITE [VANDF]
Common Name English
POTASSIUM PENTAOXODISULFATE
Common Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-224
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
JECFA EVALUATION INS-224
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
Code System Code Type Description
MESH
C005199
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
ChEMBL
CHEMBL2021714
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
MERCK INDEX
m9036
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY Merck Index
ECHA (EC/EINECS)
240-795-3
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
EPA CompTox
DTXSID1021293
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
DAILYMED
65OE787Q7W
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
SMS_ID
100000076168
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
WIKIPEDIA
POTASSIUM METABISULFITE
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
RXCUI
1362899
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY RxNorm
FDA UNII
65OE787Q7W
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
CAS
16731-55-8
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
EVMPD
SUB16065MIG
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
HSDB
5062
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
PUBCHEM
28019
Created by admin on Fri Dec 15 15:56:56 UTC 2023 , Edited by admin on Fri Dec 15 15:56:56 UTC 2023
PRIMARY
Related Record Type Details
Structure of METABISULFITE ION
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