POTASSIUM METABISULFITE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2K.O5S2
Molecular Weight	222.324
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K+].[K+].[O-]S(=O)S([O-])(=O)=O

InChI

InChIKey=RWPGFSMJFRPDDP-UHFFFAOYSA-L

InChI=1S/2K.H2O5S2/c;;1-6(2)7(3,4)5/h;;(H,1,2)(H,3,4,5)/q2*+1;/p-2

HIDE SMILES / InChI

Molecular Formula	K
Molecular Weight	39.0983
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	O5S2
Molecular Weight	144.127
Charge	-2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.food.gov.uk/business-guidance/eu-approved-additives-and-e-numbers | https://www.ncbi.nlm.nih.gov/pubmed/30031916

METABISULFITE ION is a food additive, also known as E-224. It is used as the preservative in processed fruit products including dried fruits, juices, and wine.

Approval Year

PubMed

Title	Date	PubMed
Preservation of fruit and vegetable discards with sodium metabisulfite.	2018-10-15	30031916
Effects of sodium metabisulfite on the expression of BK(Ca), K(ATP), and L-Ca(2+) channels in rat aortas in vivo and in vitro.	2015-03-02	25463229

Sample Use Guides

In Vitro Use Guide

The purpose of the study was to investigate the effect of sodium metabisulfite (SMB) on the expression of big-conductance Ca(2+)-activated K(+) (BKCa), ATP-sensitive K(+) (KATP), and L-type calcium (L-Ca(2+)) channels in rat aorta in vivo and in vitro. The results showed that the mRNA and protein levels of the BKCa channel subunits α and β1 of the aorta in rats were increased by SMB in vivo and in vitro. Similarly, the expression of the KATP channel subunits Kir6.1, Kir6.2, and SUR2B were increased by SMB. However, SMB at the highest concentration significantly decreased the expression of the L-Ca(2+) channel subunits Cav1.2 and Cav1.3.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:14:14 GMT 2025` Edited by `admin` on `Mon Mar 31 18:14:14 GMT 2025`
Record UNII	65OE787Q7W
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

E-224

Preferred Name

English

POTASSIUM METABISULFITE

Official Name

English

POTASSIUM METABISULFITE [EP IMPURITY]

Common Name

English

SOBISU

Common Name

English

POTASSIUM DISULFITE

Systematic Name

English

Potassium metabisulfite [WHO-DD]

Common Name

English

POTASSIUM METABISULFITE [EP MONOGRAPH]

Common Name

English

POTASSIUM METABISULFITE [HSDB]

Common Name

English

POTASSIUM METABISULFITE [II]

Common Name

English

Dipotassium pyrosulfite

Systematic Name

English

POTASSIUM METABISULFITE [FCC]

Common Name

English

POTASSIUM METABISULFITE [MI]

Common Name

English

POTASSIUM METABISULPHITE

Systematic Name

English

POTASSIUM METABISULFITE [MART.]

Common Name

English

POTASSIUM PYROSULFITE

Systematic Name

English

POTASSIUM METABISULFITE (E 224)

Common Name

English

FERTISILO

Common Name

English

INS-224

Common Name

English

POTASSIUM METABISULFITE [VANDF]

Common Name

English

POTASSIUM PENTAOXODISULFATE

Common Name

English

Classification Tree Code System Code

CODEX ALIMENTARIUS (GSFA)

INS-224