R-112 DISODIUM

[NaH].[NaH].OC1=CC(NC2=NC=C(F)C(NC3=CC=CC(O)=C3)=N2)=CC=C1

InChIKey=PTULPNDUGQKKCI-UHFFFAOYSA-N

InChI=1S/C16H13FN4O2.2Na.2H/c17-14-9-18-16(20-11-4-2-6-13(23)8-11)21-15(14)19-10-3-1-5-12(22)7-10;;;;/h1-9,22-23H,(H2,18,19,20,21);;;;

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Potency
Tyrosine-protein kinase SYK 21 Target ID: CHEMBL2599 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297	Inhibitor 8297	226.0 nM [IC50]
Leukotriene C4 production 2 Target ID: Leukotriene C4 production Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297	Blocker 537
mast cell activation 6 Target ID: GO:0045576 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297	Inhibitor 8297

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:27:18 GMT 2023` Edited by `admin` on `Sat Dec 16 10:27:18 GMT 2023`
Record UNII	65BJP9FDE9
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

R-112 DISODIUM

Common Name

English

R-921218 DISODIUM SALT

Common Name

English

PHENOL, 3,3'-((5-FLUORO-2,4-PYRIMIDINEDIYL)DIIMINO)BIS-, SODIUM SALT (1:2)

Systematic Name

English

3-((5-FLUORO-2-(3-HYDROXYANILINO)PYRIMIDIN-4-YL)AMINO)PHENOL; SODIUM HYDRIDE

Systematic Name

English

Code System Code Type Description

CAS

575476-11-8

Created by admin on Sat Dec 16 10:27:18 GMT 2023 , Edited by admin on Sat Dec 16 10:27:18 GMT 2023

PRIMARY

FDA UNII

65BJP9FDE9

Created by admin on Sat Dec 16 10:27:18 GMT 2023 , Edited by admin on Sat Dec 16 10:27:18 GMT 2023

PRIMARY