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Details

Stereochemistry ACHIRAL
Molecular Formula C30H40N4.2C7H5O3
Molecular Weight 730.8927
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEQUALINIUM SALICYLATE

SMILES

Cc1cc(=N)c2ccccc2n1CCCCCCCCCCn3c(C)cc(=N)c4ccccc43.c1ccc(c(c1)C(=O)O)O.c1ccc(c(c1)C(=O)O)O

InChI

InChIKey=KJKANYXQJTTYMC-UHFFFAOYSA-N
InChI=1S/C30H38N4.2C7H6O3/c1-23-21-27(31)25-15-9-11-17-29(25)33(23)19-13-7-5-3-4-6-8-14-20-34-24(2)22-28(32)26-16-10-12-18-30(26)34;2*8-6-4-2-1-3-5(6)7(9)10/h9-12,15-18,21-22,31-32H,3-8,13-14,19-20H2,1-2H3;2*1-4,8H,(H,9,10)

HIDE SMILES / InChI

Molecular Formula C7H6O3
Molecular Weight 138.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C30H38N4
Molecular Weight 454.6506
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment:: https://www.drugs.com/uk/fluomizin-10-mg-vaginal-tablets-leaflet.html | https://www.drugs.com/pro/salicylic-acid.html

Dequalinium salicylate is a bisquanternary quinolinium antiseptic which kills many gram-positive and gram-negative bacteria. Dequalinium Salicylate have antibacterial (mediated by Dequalinium action) and anti-inflammatory activities (mediated by Salicylic acid action). Dequalinium has an antiseptic effect against a wide range of bacteria, yeasts, and some fungi and viruses. It kills the micro-organisms associated with various mild infections of the mouth and throat. Salicylic acid have direct anti-inflammatory activity mediated by inhibition of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid.

Originator

Sources: JP41018231

Approval Year

PubMed

PubMed

TitleDatePubMed
[Studies on antifungal substances. VII. Studies on the solubility of various dequalinium salts. (1). Solubility of dequalinium salicylate, chloride in water-proplene glycol-ethanol systems].
1967 Jan
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 09:40:40 UTC 2021
Edited
by admin
on Sat Jun 26 09:40:40 UTC 2021
Record UNII
65A568ZIJ4
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEQUALINIUM SALICYLATE
WHO-DD  
Common Name English
DEQUALINIUM SALYCILATE [JAN]
Common Name English
SALICYLIC ACID, ION(1-), 1,1'-DECAMETHYLENEBIS(4-AMINOQUINALDINIUM)
Common Name English
QUINOLINIUM, 1,1'-(1,10-DECANEDIYL)BIS(4-AMINO-2-METHYL-, 2-HYDROXYBENZOATE (1:2)
Common Name English
DEQUALINIUM SALICYLATE [WHO-DD]
Common Name English
DEQUALINIUM SALYCILATE
JAN  
Common Name English
Code System Code Type Description
ECHA (EC/EINECS)
240-157-4
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
RXCUI
236549
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY RxNorm
EVMPD
SUB01592MIG
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
FDA UNII
65A568ZIJ4
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
CAS
16022-70-1
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
EPA CompTox
16022-70-1
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
PUBCHEM
54683736
Created by admin on Sat Jun 26 09:40:40 UTC 2021 , Edited by admin on Sat Jun 26 09:40:40 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE