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Details

Stereochemistry ACHIRAL
Molecular Formula 2Na.O4W
Molecular Weight 293.82
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM TUNGSTATE

SMILES

[Na+].[Na+].[O-][W]([O-])(=O)=O

InChI

InChIKey=XMVONEAAOPAGAO-UHFFFAOYSA-N
InChI=1S/2Na.4O.W/q2*+1;;;2*-1;

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula O4W
Molecular Weight 247.84
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Tungstic acid is a fairly strong acid, it catalyzes the oxidation by hydrogen peroxide of alkenes to the corresponding epoxides. Tungstic acid is widely used in the production of tungsten metal, alloys, and is used as a mordant for textiles and plastics. Tungstic acid has been reported to rapidly precipitate the quaternary ammonium cations in cholinergic nerve terminals, such as ACh or choline. Also, tungsten dietary supplementation has successfully been used to reduce xanthine oxide (XO) activity, resulting in decreased gastrointestinal (GI) mucosal damage because of lowered XO activity. Tungstic acid has been shown to effectively antagonize stress-induced gastric ulcers, possibly by decreasing motility and mass cell degranulation. Tungstic acid gel has been used as an epileptogenic agent since 1960. Epilepsy produced by this agent is characterized by good localization, short latency and limited duration. It is effective in cerebral cortex, brain stem and spinal cord.

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
The preparation of tungstic acid gel and its use in the production of experimental epilepsy.
1967 Mar
Streamline pattern and velocity components of flow in a model of a branching coronary vessel--possible functional implication for the development of localized platelet deposition in vitro.
1986 Mar
Tungstic acid reduction of cold-resistant stress-induced ulceration in rats.
1997 Jan
Protective effects of tungstophosphoric acid and sodium tungstate on chemically induced liver necrosis in wistar rats.
2007
The potential reproductive, neurobehavioral and systemic effects of soluble sodium tungstate exposure in Sprague-Dawley rats.
2011 Jul 15
Exposure to sodium tungstate and Respiratory Syncytial Virus results in hematological/immunological disease in C57BL/6J mice.
2012 Apr 5
Genotoxic changes to rodent cells exposed in vitro to tungsten, nickel, cobalt and iron.
2014 Mar 10
Tungsten-induced carcinogenesis in human bronchial epithelial cells.
2015 Oct 1

Sample Use Guides

In Vivo Use Guide
Sprague-Dawley rats were restrained at 4 degrees C for 2 h (stress). Tungstic acid in a single dose of 0.01, 0.1, 1, 10, 100 or 300 mg/kg (dissolved in distilled water) was administered intragastrically to animals 30 min prior to stress. Doses of tungstic acid of 1 mg/kg and higher significantly decreased ulcers.
Route of Administration: Intragastric
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:15:43 GMT 2023
Edited
by admin
on Sat Dec 16 08:15:43 GMT 2023
Record UNII
64LRH4405G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM TUNGSTATE
Common Name English
TUNGSTIC ACID (H2WO4), DISODIUM SALT
Common Name English
SODIUM TUNGSTATE(VI) [MI]
Common Name English
TUNGSTATE (WO42-), SODIUM (1:2), (T-4)-
Common Name English
DISODIUM TUNGSTATE
Common Name English
SODIUM TUNGSTEN OXIDE (NA2WO4)
Common Name English
SODIUM TUNGSTATE(VI)
MI  
Common Name English
DISODIUM TETRAOXOTUNGSTATE(2-)
Common Name English
DISODIUM TETRAOXATUNGSTATE(2-)
Common Name English
Code System Code Type Description
WIKIPEDIA
SODIUM TUNGSTATE
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY
HSDB
5057
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
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CHEBI
63940
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
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CAS
13472-45-2
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
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ECHA (EC/EINECS)
236-743-4
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY
PUBCHEM
26052
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY
SMS_ID
300000042577
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY
FDA UNII
64LRH4405G
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY
MERCK INDEX
m10096
Created by admin on Sat Dec 16 08:15:43 GMT 2023 , Edited by admin on Sat Dec 16 08:15:43 GMT 2023
PRIMARY Merck Index
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