N-METHYLPHTHALIMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7NO2
Molecular Weight	161.1574
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CN1C(=O)C2=C(C=CC=C2)C1=O

InChI

InChIKey=ZXLYYQUMYFHCLQ-UHFFFAOYSA-N

InChI=1S/C9H7NO2/c1-10-8(11)6-4-2-3-5-7(6)9(10)12/h2-5H,1H3

HIDE SMILES / InChI

Molecular Formula	C9H7NO2
Molecular Weight	161.1574
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.dea.gov/pr/microgram-journals/2011/mj8-2_26-38.pdf

N-methylphthalimide (NMP) is an indole-based heterocyclic compound traditionally used as an intermediate for organic syntheses or as a building block for plastics and dyes. There are no known medical uses for NMP.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Synergistic antiviral effect of PEG-asparaginase (ONCASPAR), with protease inhibitor alone and in combination with RT inhibitors against HIV-1 infected T-cells: a model of HIV-1-induced T-cell lymphoma.	2001 Jan-Feb	11286117
Sorption and degradation characteristics of phosmet in two contrasting Australian soils.	2002 Sep-Oct	12371180
Cell handling, membrane-binding properties, and membrane-penetration modeling approaches of pivampicillin and phthalimidomethylampicillin, two basic esters of ampicillin, in comparison with chloroquine and azithromycin.	2003 Apr	12739771
Synthesis and biological activity of pyridinium-type acetylcholinesterase inhibitors.	2003 Oct	14607022
Intracellular accumulation and activity of ampicillin used as free drug and as its phthalimidomethyl or pivaloyloxymethyl ester (pivampicillin) against Listeria monocytogenes in J774 macrophages.	2003 Oct	12972457
Photolysis experiments on phosmet, an organophosphorus insecticide.	2003 Sep 24	13129307
Synthesis of cycloalkynes via photochemical decarboxylation of omega-phthalimidoalkynoates.	2004 Mar	14993949
Titanocene-catalyzed coupling of aromatic amides in the presence of organosilanes: a novel route to vicinal diamines and a new class of amine-substituted oligomers.	2004 Oct 1	15387610
Electroreductive coupling of phthalimides with alpha,beta-unsaturated esters: unusual rearrangement of resulting silyl ketene acetals.	2009 Nov 5	19780541

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

The rate constant for triplet quenching of N-methylphthalimide is k(q) < 10(7) M(-1) s(-1) for 2-phenylacetic acid and k(q) = (1-3) x 10(9) M(-1) s(-1) for its mono-, di- and trimethoxy-substituted derivatives.

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:08:28 GMT 2023` Edited by `admin` on `Sat Dec 16 02:08:28 GMT 2023`
Record UNII	647UP45J2U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

N-METHYLPHTHALIMIDE

Systematic Name

English

1H-ISOINDOLE-1,3(2H)-DIONE, 2-METHYL-

Systematic Name

English

2-METHYL-ISOINDOLE-1,3-DIONE

Systematic Name

English

N-METHYL PHTHALIMIDE

Systematic Name

English

NSC-44059

Code

English

Code System Code Type Description

EPA CompTox

DTXSID5027198