U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Wed Apr 02 10:15:27 GMT 2025
Edited
by admin
on Wed Apr 02 10:15:27 GMT 2025
Nucleic Acid Type OLIGONUCLEOTIDE
Sequence Origin SYNTHETIC
Sequence Type COMPLETE
Record UNII
646C2NRN3Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DNA, d([2?-O-(2-methoxyethyl)](m<sup>5</sup>rC-sp-m<sup>5</sup>rC-rA-<sup>5</sup>rC-rG-rA)-<sup>5</sup>C-s<sup>p</sup>-A-s<sup>p</sup>-T-<sup>p</sup>-A-<sup>p</sup>-T-<sup>p</sup>-T-<sup>p</sup>-T-<sup>p</sup>-T-<sup>p</sup>-T-<sup>p</sup>-m<sup>5</sup>C
Preferred Name English
Elsunersen sodium
Common Name English
Code System Code Type Description
FDA UNII
646C2NRN3Y
Created by admin on Wed Apr 02 10:15:27 GMT 2025 , Edited by admin on Wed Apr 02 10:15:27 GMT 2025
PRIMARY
CAS
2755996-85-9
Created by admin on Wed Apr 02 10:15:27 GMT 2025 , Edited by admin on Wed Apr 02 10:15:27 GMT 2025
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_7-1_16 10 / 20
2'-O-Methoxyethyl ribose 1_1-1_6;1_17-1_20 10 / 20
Linkage Site Range Site Count
Sodium Phosporothioate 1_2;1_8-1_17;1_19-1_20 13 / 19
1_3-1_7;1_18 6 / 19
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE BASE SUBSTITUTION [1_17] THYMINE QR26YLT7LT
NUCLEOSIDE BASE SUBSTITUTION [1_1] [1_2] [1_4] [1_7] [1_16] [1_19] 5-METHYLCYTOSINE 6R795CQT4H