SIRUKUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 20:31:48 GMT 2025` Edited by `admin` on `Mon Mar 31 20:31:48 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	640443FU93
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SIRUKUMAB

Official Name

English

sirukumab [INN]

Preferred Name

English

CNTO136

Code

English

SIRUKUMAB [USAN]

Common Name

English

SIRUKUMAB [JAN]

Common Name

English

Sirukumab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN INTERLEUKIN 6) (HUMAN MONOCLONAL CNTO 136 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CNTO 136 .KAPPA.-CHAIN, DIMER

Common Name

English

CNTO-136

Code

English

Classification Tree Code System Code

WHO-ATC

L04AC15

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

FDA ORPHAN DRUG

575217

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

NCI_THESAURUS

C20401

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

NCI_THESAURUS

C574

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

Code System Code Type Description

WIKIPEDIA

SIRUKUMAB

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

SMS_ID

100000164554

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

USAN

XX-75

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

ChEMBL

CHEMBL1743071

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

EVMPD

SUB179011

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

CAS

1194585-53-9

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

NCI_THESAURUS

C152371

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

FDA UNII

640443FU93

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

DRUG BANK

DB11803

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

INN

9431

Created by admin on Mon Mar 31 20:31:48 GMT 2025 , Edited by admin on Mon Mar 31 20:31:48 GMT 2025

PRIMARY

From	To
1_22	1_96
1_146	1_202
1_263	1_323
1_369	1_427
2_22	2_96
2_146	2_202
2_263	2_323
2_369	2_427
3_23	3_87
3_133	3_193
4_23	4_87
4_133	4_193
1_222	3_213
2_222	4_213
1_228	2_228
1_231	2_231

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					156G191JXJ

INTERLEUKIN 6 RECEPTOR

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					640443FU93

SIRUKUMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL