APOPTOSIS REGULATOR BCL-X

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 03:32:05 GMT 2025` Edited by `admin` on `Wed Apr 02 03:32:05 GMT 2025`
Protein Type	REGULATOR PROTEIN
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	63L54VY2VT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

APOPTOSIS REGULATOR BCL-X

Common Name

English

B-CELL LYMPHOMA-EXTRA LARGE

Preferred Name

English

BCL-XL

Common Name

English

BCL2-L-1

Common Name

English

BCL-2-LIKE PROTEIN 1

Common Name

English

BCLX

Common Name

English

Code System Code Type Description

FDA UNII

63L54VY2VT

Created by admin on Wed Apr 02 03:32:05 GMT 2025 , Edited by admin on Wed Apr 02 03:32:05 GMT 2025

PRIMARY

UNIPROT

Q07817

Created by admin on Wed Apr 02 03:32:05 GMT 2025 , Edited by admin on Wed Apr 02 03:32:05 GMT 2025

PRIMARY

Related Record Type Details


					317UBD60ML

PELCITOCLAX

INHIBITOR -> TARGET

Amount:


					VT53CL5GES

Foselutoclax

INHIBITOR -> TARGET

Amount:


					Y8JQ9V7JAJ

DT-2216

DEGRADER, SELECTIVE->TARGET

Comments:

a von Hippel-Landau (VHL)-recruiting PROTAC; maximum degradation (Dmax) of 90.8%, and the degradation was dependent on both VHL and proteasome. MOLT-4 T-cell acute lymphoblastic leukemia (T-ALL) cells

Qualification:

DC50

Amount:


					OSL3FEZ1IF

LISAFTOCLAX

INHIBITOR -> TARGET

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL