U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C20H12
Molecular Weight 252.3093
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENZO(E)PYRENE

SMILES

C1=CC=C2C(=C1)C3=C4C(C=CC5=CC=CC2=C45)=CC=C3

InChI

InChIKey=TXVHTIQJNYSSKO-UHFFFAOYSA-N
InChI=1S/C20H12/c1-2-8-16-15(7-1)17-9-3-5-13-11-12-14-6-4-10-18(16)20(14)19(13)17/h1-12H

HIDE SMILES / InChI

Molecular Formula C20H12
Molecular Weight 252.3093
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Cardiac toxicity of 5-ring polycyclic aromatic hydrocarbons is differentially dependent on the aryl hydrocarbon receptor 2 isoform during zebrafish development.
2011-12-01
Reduced cytochrome P4501A activity and recovery from oxidative stress during subchronic benzo[a]pyrene and benzo[e]pyrene treatment of rainbow trout.
2011-07-01
Antioxidant airway responses following experimental exposure to wood smoke in man.
2010-08-20
Influence of temperature and origin of dissolved organic matter on the partitioning behavior of polycyclic aromatic hydrocarbons.
2010-06
Inhibition of apoptosis in human retinal pigment epithelial cells treated with benzo(e)pyrene, a toxic component of cigarette smoke.
2010-05
Malondialdehyde-modified low density lipoprotein (MDA-LDL)-induced cell growth was suppressed by polycyclic aromatic hydrocarbons (PAHs).
2010-04
Navajo coal combustion and respiratory health near Shiprock, New Mexico.
2010
3-methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats.
2009-12
Oligothiophene functionalized dimethyldihydropyrenes I: syntheses and photochromicity.
2009-09-04
Inhibition of human mesenchymal stem cell-derived adipogenesis by the environmental contaminant benzo(a)pyrene.
2009-09
Effects of benzo(e)pyrene on the retinal neurosensory cells and human microvascular endothelial cells in vitro.
2009-08
Polycyclic aromatic hydrocarbons in Tripuí River, Ouro Preto, MG, Brazil.
2009-06-15
Role of a moderately halophilic bacterial consortium in the biodegradation of polyaromatic hydrocarbons.
2009-02
[Ah receptor-independent inhibition of gap junction intercellular communications in hepatoma cell culture 27 by polycyclic aromatic hydrocarbons].
2009
Rapid SPE-HPLC determination of the 16 European priority polycyclic aromatic hydrocarbons in olive oils.
2008-12
Polycyclic aromatic hydrocarbons in spanish olive oils: relationship between benzo(a)pyrene and total polycyclic aromatic hydrocarbon content.
2008-11-12
Effects of Benzo(e)Pyrene, a toxic component of cigarette smoke, on human retinal pigment epithelial cells in vitro.
2008-11
The response of Ty1 test to genotoxins.
2008-10
Size distribution of particle-phase molecular markers during a severe winter pollution episode.
2008-09-01
Experimental approaches to evaluate activities of cytochromes P450 3A.
2008-09
VOCs and PAHs emissions from creosote-treated wood in a field storage area.
2008-08-25
Enhanced kinetics of solid-phase microextraction and biodegradation of polycyclic aromatic hydrocarbons in the presence of dissolved organic matter.
2008-07
Photochemical degradation of polycyclic aromatic hydrocarbons in oil films.
2008-04-01
Fluorescence study of inclusion complexes between star-shaped cholic acid derivatives and polycyclic aromatic fluorescent probes and the size effects of host and guest molecules.
2008-03-20
Unexpected DNA damage caused by polycyclic aromatic hydrocarbons under standard laboratory conditions.
2008-02-29
Optimization of the matrix solid-phase dispersion sample preparation procedure for analysis of polycyclic aromatic hydrocarbons in soils: comparison with microwave-assisted extraction.
2007-09-21
The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis.
2007-08-01
Effects of benzo(e)pyrene and benzo(a)pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer: a comparative approach.
2007-08
Oxidized metabolites from benzo[a]pyrene, benzo[e]pyrene, and aza-benzo[a]pyrenes. A computational study of their carbocations formed by epoxide ring opening reactions.
2007-07-21
UVA photoirradiation of methylated benzo[a]pyrene and benzo[e]pyrene leading to induction of lipid peroxidation.
2007-06
Trophic dilution of polycyclic aromatic hydrocarbons (PAHs) in a marine food web from Bohai Bay, north China.
2007-05-01
[Determination of trace polycyclic aromatic hydrocarbons in surface sediments of Huangpu River by high performance liquid chromatography].
2007-05
Benzo[a]pyrene-dependent activation of transcription factors NF-kappaB and AP-1 related to tumor promotion in hepatoma cell cultures.
2007-05
Sample preparation of sewage sludge and soil samples for the determination of polycyclic aromatic hydrocarbons based on one-pot microwave-assisted saponification and extraction.
2007-04
Microheterogeneity evaluation of polycyclic aromatic hydrocarbons in particulate standard reference materials.
2007-04
Source apportionment of molecular markers and organic aerosol--1. Polycyclic aromatic hydrocarbons and methodology for data visualization.
2006-12-15
Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.
2006-10-16
Polycyclic aromatic hydrocarbons in food samples collected in Barcelona, Spain.
2006-08
Electron affinities of polycyclic aromatic hydrocarbons by means of B3LYP/6-31+G* calculations.
2006-05-25
Distribution of pesticides, PAHs and heavy metals in prawn ponds near Kolleru lake wetland, India.
2006-04
Optimization of the procedure for the determination of polycyclic aromatic hydrocarbons and their derivatives in fish tissue: Estimation of measurements uncertainty.
2006-03
Phenacenes from Diels-Alder trapping of photogenerated o-xylylenols: phenanthrenes and benzo[e]pyrene bisimide.
2006-02-16
Physicochemical characterisation of combustion particles from vehicle exhaust and residential wood smoke.
2006-01-03
Detection of initiating as well as promoting activity of chemicals by a novel cell transformation assay using v-Ha-ras-transfected BALB/c 3T3 cells (Bhas 42 cells).
2005-12-07
Further evaluation of the skin micronucleus test: results obtained using 10 polycyclic aromatic hydrocarbons.
2005-12-07
Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor.
1997-08-22
Metabolic requirements for induction of contact hypersensitivity to immunotoxic polyaromatic hydrocarbons.
1995-10-01
Induction of CYP1A1 gene expression in mouse hepatoma cells by benzo[e]pyrene, a ligand of the 4S polycyclic hydrocarbon-binding protein.
1994-09
Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons.
1988-12
Binding of polynuclear aromatic hydrocarbons to the rat 4S cytosolic binding protein: structure-activity relationships.
1987-02
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:47:20 GMT 2025
Edited
by admin
on Mon Mar 31 18:47:20 GMT 2025
Record UNII
63APT6398R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-89273
Preferred Name English
BENZO(E)PYRENE
HSDB   MI  
Systematic Name English
BENZO(E)PYRENE [MI]
Common Name English
BENZO(E)PYRENE [IARC]
Common Name English
1,2-BENZPYRENE
Common Name English
4,5-BENZPYRENE
Common Name English
BENZO(E)PYRENE [HSDB]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID3023764
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
MESH
C026487
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
CAS
192-97-2
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
ECHA (EC/EINECS)
205-892-7
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
FDA UNII
63APT6398R
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
SMS_ID
300000053134
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
CHEBI
34567
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
WIKIPEDIA
BENZO(E)PYRENE
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
NSC
89273
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
HSDB
4031
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY
MERCK INDEX
m2377
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY Merck Index
PUBCHEM
9128
Created by admin on Mon Mar 31 18:47:20 GMT 2025 , Edited by admin on Mon Mar 31 18:47:20 GMT 2025
PRIMARY