1-ANILINO-8-NAPHTHALENESULFONIC ACID

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H13NO3S
Molecular Weight	299.344
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1-ANILINO-8-NAPHTHALENESULFONIC ACID

Structure Search

SMILES

OS(=O)(=O)C1=CC=CC2=C1C(NC3=CC=CC=C3)=CC=C2

InChI

InChIKey=FWEOQOXTVHGIFQ-UHFFFAOYSA-N

InChI=1S/C16H13NO3S/c18-21(19,20)15-11-5-7-12-6-4-10-14(16(12)15)17-13-8-2-1-3-9-13/h1-11,17H,(H,18,19,20)

HIDE SMILES / InChI

Molecular Formula	C16H13NO3S
Molecular Weight	299.344
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Transthyretin 6 Target ID: CHEMBL3194 Sources: https://www.ncbi.nlm.nih.gov/pubmed/19954984	Binding Agent 1076		1.1 µM [Kd]

PubMed

Title	Date	PubMed
The major birch allergen, Bet v 1, shows affinity for a broad spectrum of physiological ligands.	2002-06-28	11953433
Pathway complexity of prion protein assembly into amyloid.	2002-06-14	11912192
Converting troponin C into calmodulin: effects of mutations in the central helix and of changes in temperature.	2002-06	11943596
Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability.	2002-06	11943595
Amyloid-like fibril formation in an all beta-barrel protein involves the formation of partially structured intermediate(s).	2002-05-24	11877422
Guanidinium chloride induced unfolding of a hemocyanin subunit from Carcinus aestuarii. I. Apo form.	2002-05-20	12009401
Methionine oxidation as a major cause of the functional impairment of oxidized actin.	2002-05-01	11978495
Oligomerization process of the hemolytic lectin CEL-III purified from a sea cucumber, Cucumaria echinata.	2002-05	11983084
Thioridazine interacts with the membrane of mitochondria acquiring antioxidant activity toward apoptosis--potentially implicated mechanisms.	2002-05	11976278
Role of individual disulfide bonds in hen lysozyme early folding steps.	2002-05	11967370
Thermodynamics of the ligandin function of human class Alpha glutathione transferase A1-1: energetics of organic anion ligand binding.	2002-04-15	11931663
The refolding of type II shikimate kinase from Erwinia chrysanthemi after denaturation in urea.	2002-04	11985590
Amyloid fibril formation of the mouse V(L) domain at acidic pH.	2002-03-12	11876647
Inactivation of NADP(+)-dependent isocitrate dehydrogenase by reactive oxygen species.	2002-03-07	11879734
Probing reactive center loop insertion in serpins: a simple method for ovalbumin.	2002-03-01	11846379
Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin.	2002-02-27	11904158
Dendritic galactosides based on a beta-cyclodextrin core for the construction of site-specific molecular delivery systems: synthesis and molecular recognition studies.	2002-02-15	11857696
Testing of the portal hypothesis: analysis of a V32G, F57G, K58G mutant of the fatty acid binding protein of the murine adipocyte.	2002-02-12	11827549
Adsorptive immobilization of intestinal brush border membrane on Triton X-100-substituted Sepharose 4B.	2002-02	11996226
Equilibrium unfolding studies of the rat liver methionine adenosyltransferase III, a dimeric enzyme with intersubunit active sites.	2002-01-15	11772402
Highly divergent dihydrofolate reductases conserve complex folding mechanisms.	2002-01-11	11779239
The alphaA-crystallin R116C mutant has a higher affinity for forming heteroaggregates with alphaB-crystallin.	2002-01-08	11772029
Unique oligomeric intermediates of bovine liver catalase.	2002-01	11742121
Temperature-induced formation of a non-native intermediate state of the all beta-sheet protein CD2.	2002	11939369
Role of the disulfide cleavage induced molten globule state of type a botulinum neurotoxin in its endopeptidase activity.	2001-12-18	11735415
Bridged bis(beta-cyclodextrin)s possessing coordinated metal center(s) and their inclusion complexation behavior with model substrates: enhanced molecular binding ability by multiple recognition.	2001-12-14	11735533
The cytochrome c fold can be attained from a compact apo state by occupancy of a nascent heme binding site.	2001-12-07	11584011
Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro.	2001-12-07	11559702
Multiple unfolding intermediates of human placental alkaline phosphatase in equilibrium urea denaturation.	2001-12	11721007
Conformational and functional significance of residue proline 17 in chicken muscle adenylate kinase.	2001-11-23	11728443
Stabilization of partially folded conformation during alpha-synuclein oligomerization in both purified and cytosolic preparations.	2001-11-23	11590163
Binding affinity properties of dendritic glycosides based on a beta-cyclodextrin core toward guest molecules and concanavalin A.	2001-11-16	11701037
Acid-induced partly folded conformation resembling a molten globule state of xylanase from an alkalothermophilic Bacillus sp.	2001-11-16	11700042
Tryptophan mutants of intestinal fatty acid-binding protein: ultraviolet absorption and circular dichroism studies.	2001-11-15	11697859
Partially folded conformations in the folding pathway of bovine carbonic anhydrase II: a fluorescence spectroscopic analysis.	2001-11-05	11948867
Molecular mechanism for osmolyte protection of creatine kinase against guanidine denaturation.	2001-11	11722578
Reversible changes of the wheat gamma 46 gliadin conformation submitted to high pressures and temperatures.	2001-11	11722554
Octyl glucoside induced formation of the molten globule-like state of glutamate dehydrogenase.	2001-11	11686930
Interaction of gramicidin with lysophosphatidylcholine as revealed by calorimetry and fluorescence spectroscopy.	2001-11	11686923
A role for aromatic amino acids in the binding of Xenopus ribosomal protein L5 to 5S rRNA.	2001-10-23	11601989
Effects of the antiplatelet agent TA-993 and its metabolite MB3 on the hemorheological properties of rat and human erythrocytes.	2001-10-15	11672754
Clusterin, a binding protein with a molten globule-like region.	2001-10-02	11570883
Artificial chaperone mediated refolding of xylanase from an alkalophilic thermophilic Bacillus sp. Implications for in vitro protein renaturation via a folding intermediate.	2001-10	11606210
Hydrophobicity of whey protein concentrates measured by fluorescence quenching and its relation with surface functional properties.	2001-10	11600022
Structural changes in natural actomyosin and surimi from ling cod (Ophiodon elongatus) during frozen storage in the absence or presence of cryoprotectants.	2001-10	11600013
A partially folded intermediate conformation is induced in pectate lyase C by the addition of 8-anilino-1-naphthalenesulfonate (ANS).	2001-10	11567103
Resonance energy transfer study of peptide-lipid complexes.	2001-09-18	11583833
Characteristics of sarcoplasmic reticulum membrane preparations isolated from skeletal muscles of active and hibernating ground squirrel Spermophilus undulatus.	2001-08	11566064
Use of reversible denaturation for adsorptive immobilization of urease.	2001-06	11563828
The nuclear matrix is a thermolabile cellular structure.	2001-04	11599575

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:19:42 GMT 2025` Edited by `admin` on `Mon Mar 31 21:19:42 GMT 2025`
Record UNII	630I4V6051
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-ANILINO-8-NAPHTHALENESULFONATE

Preferred Name

English

1-ANILINO-8-NAPHTHALENESULFONIC ACID

Systematic Name

English

8-(PHENYLAMINO)-1-NAPHTHALENESULFONIC ACID

Systematic Name

English

PHENYLPERI ACID

Common Name

English

8-ANILINO-1-NAPHTHALENESULFONIC ACID

Systematic Name

English

ANS

Common Name

English

PHENYL PERI ACID

Common Name

English

NSC-1746

Code

English

1-ANILINO-8-NAPHTHALENESULFONATE [MI]

Common Name

English

Code System Code Type Description

PUBCHEM

1369