Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C50H60Br4N6O6S2 |
| Molecular Weight | 1224.794 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(CC1=C(NC(=O)[C@H](CSSC[C@H](NC(=O)OCC2=CC=CC=C2)C(=O)NC3=C(CN(C)C4CCCCC4)C=C(Br)C=C3Br)NC(=O)OCC5=CC=CC=C5)C(Br)=CC(Br)=C1)C6CCCCC6
InChI
InChIKey=UVOSLKVETODLTR-CXNSMIOJSA-N
InChI=1S/C50H60Br4N6O6S2/c1-59(39-19-11-5-12-20-39)27-35-23-37(51)25-41(53)45(35)57-47(61)43(55-49(63)65-29-33-15-7-3-8-16-33)31-67-68-32-44(56-50(64)66-30-34-17-9-4-10-18-34)48(62)58-46-36(24-38(52)26-42(46)54)28-60(2)40-21-13-6-14-22-40/h3-4,7-10,15-18,23-26,39-40,43-44H,5-6,11-14,19-22,27-32H2,1-2H3,(H,55,63)(H,56,64)(H,57,61)(H,58,62)/t43-,44-/m0/s1
| Molecular Formula | C50H60Br4N6O6S2 |
| Molecular Weight | 1224.794 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Cistinexine is an expectorant drug developed by Italian company Recordati S.p.A. Cistinexine as a cystine derivative that has shown an expectorant action similar to bromhexine during preclinical pharmacological trials. In clinical trials in patients with chronic bronchitis, treatment with cistinexine did not lead to a reduction of mucus transport rate (MTR). The only significant effect was observed in patients with severe impairment of MTR.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:02:10 GMT 2023
by
admin
on
Fri Dec 15 16:02:10 GMT 2023
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| Record UNII |
62VR67FK8E
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C74536
Created by
admin on Fri Dec 15 16:02:10 GMT 2023 , Edited by admin on Fri Dec 15 16:02:10 GMT 2023
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NCI_THESAURUS |
C29767
Created by
admin on Fri Dec 15 16:02:10 GMT 2023 , Edited by admin on Fri Dec 15 16:02:10 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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65644
Created by
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CHEMBL2106053
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86042-50-4
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5822
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C048720
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SUB07484MIG
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62VR67FK8E
Created by
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DTXSID50235360
Created by
admin on Fri Dec 15 16:02:10 GMT 2023 , Edited by admin on Fri Dec 15 16:02:10 GMT 2023
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100000081546
Created by
admin on Fri Dec 15 16:02:10 GMT 2023 , Edited by admin on Fri Dec 15 16:02:10 GMT 2023
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C77595
Created by
admin on Fri Dec 15 16:02:10 GMT 2023 , Edited by admin on Fri Dec 15 16:02:10 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
