U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C8H8O5
Molecular Weight 184.1461
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of METHYL GALLATE

SMILES

COC(=O)C1=CC(O)=C(O)C(O)=C1

InChI

InChIKey=FBSFWRHWHYMIOG-UHFFFAOYSA-N
InChI=1S/C8H8O5/c1-13-8(12)4-2-5(9)7(11)6(10)3-4/h2-3,9-11H,1H3

HIDE SMILES / InChI

Molecular Formula C8H8O5
Molecular Weight 184.1461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
[Chemical constitutents of Bauhinia aurea].
2006 Dec
[Studies on HPLC fingerprint of cortex moutan].
2006 Oct
Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages.
2007
Profiling and characterization by LC-MSn of the galloylquinic acids of green tea, tara tannin, and tannic acid.
2007 Apr 18
alpha-Glucosidase inhibitory constituents from stem bark of Terminalia superba (Combretaceae).
2007 Aug
[HPLC fingerprinting of radix paeoniae alba].
2007 Jan
Anticancer and antioxidant tannins from Pimenta dioica leaves.
2007 Jul-Aug
New dihydrochalcones and anti-platelet aggregation constituents from the leaves of Muntingia calabura.
2007 Jun
Mutagenic evaluation and chemical investigation of Byrsonima intermedia A. Juss. leaf extracts.
2007 Jun 13
Constituents and antiulcer effect of Alchornea glandulosa: activation of cell proliferation in gastric mucosa during the healing process.
2007 Mar
Effect of compounds of Galla chinensis on remineralisation of initial enamel carious lesions in vitro.
2007 May
High-added-value antioxidants obtained from the degradation of wine phenolics by Lactobacillus plantarum.
2007 Nov
Purification and characterization of two cold-adapted extracellular tannin acyl hydrolases from an Antarctic strain Verticillium sp. P9.
2007 Nov
Anti-HSV-1 and anti-HIV-1 activity of gallic acid and pentyl gallate.
2008 Aug
Inhibitory effect of methyl gallate and gallic acid on oral bacteria.
2008 Dec
Witch hazel (Hamamelis virginiana) fractions and the importance of gallate moieties--electron transfer capacities in their antitumoral properties.
2008 Dec 24
A new cytotoxic acylated apigenin glucoside from Phyllanthus emblica L.
2008 Jan 10
Characterization of tannase activity in cell-free extracts of Lactobacillus plantarum CECT 748T.
2008 Jan 15
Characterization and quantitation of polyphenolic compounds in bark, kernel, leaves, and peel of mango (Mangifera indica L.).
2008 Jul 23
Stopped-flow kinetic study of the aroxyl radical-scavenging action of catechins and vitamin C in ethanol and micellar solutions.
2008 Jun 25
Antioxidative compounds from Quercus salicina Blume stem.
2008 Mar
Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays.
2008 Mar
[Inhibitive effect of extracts of Galla Chinesis on caries development in rats].
2008 May
In vitro activity of methyl gallate isolated from galla rhois alone and in combination with ciprofloxacin against clinical isolates of salmonella.
2008 Nov
Inhibitory effect of macabarterin, a polyoxygenated ellagitannin from Macaranga barteri, on human neutrophil respiratory burst activity.
2008 Nov
The anti-allergic activity of the acetate fraction of Schinus terebinthifolius leaves in IgE induced mice paw edema and pleurisy.
2008 Nov
1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Galla Rhois protects primary rat hepatocytes from necrosis and apoptosis.
2008 Sep
Separation and purification of two flavone glucuronides from Erigeron multiradiatus (Lindl.) Benth with macroporous resins.
2009
Methyl gallate is a natural constituent of maple (Genus Acer) leaves.
2009
Components derived from Pelargonium stimulate macrophage killing of Mycobacterium species.
2009 Apr
Antioxidant and hepatoprotective activities of thai mango seed kernel extract.
2009 Aug
Effects of methyl gallate and gallic acid on the production of inflammatory mediators interleukin-6 and interleukin-8 by oral epithelial cells stimulated with Fusobacterium nucleatum.
2009 Dec
Magnoflorine and phenolic derivatives from the leaves of Croton xalapensis L. (Euphorbiaceae).
2009 Dec
Antioxidants from the leaf extract of Byrsonima bucidaefolia.
2009 Jan
Ellagitannins from Terminalia calamansanai induced apoptosis in HL-60 cells.
2009 Jun
[Studies on the chemical constituents from Xinjiang Punica granatum].
2009 Mar
Antibacterial activity of methyl gallate isolated from Galla Rhois or carvacrol combined with nalidixic acid against nalidixic acid resistant bacteria.
2009 May 11
Characterisation of tannin-containing herbal drugs by HPLC.
2009 May-Jun
Qualitative and quantitative determination of hydrolysable tannins and other polyphenols in herbal products from meadowsweet and dog rose.
2009 May-Jun
New phthalates from Phyllanthus muellerianus (Euphorbiaceae).
2009 Nov
Diterpene esters and phenolic compounds from Sapium insigne (ROYLE) BENTH. ex HOOK. fil.
2009 Nov
[Chemical constituents from roots of Distylium myricoides].
2009 Sep
Protective effects of polyphenolic compounds on oxidative stress-induced cytotoxicity in PC12 cells.
2010 Apr
Ellagitannins from Geranium potentillaefolium and G. bellum.
2010 Apr
Multifactorial anticancer effects of digalloyl-resveratrol encompass apoptosis, cell-cycle arrest, and inhibition of lymphendothelial gap formation in vitro.
2010 Apr 27
Structural characteristics for superoxide anion radical scavenging and productive activities of green tea polyphenols including proanthocyanidin dimers.
2010 Jan
Geraniinic acid derivative from the leaves of Phyllanthus reticulatus.
2010 Jul
Antioxidant effects of secondary metabolites from Geranium psilostemon.
2010 Jun
Secondary plant substances in various extracts of the leaves, fruits, stem and bark of Caraipa densifolia Mart.
2010 Jun
Protective effects of methyl gallate on H2O2-induced apoptosis in PC12 cells.
2010 Mar 19
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:41:58 GMT 2023
Edited
by admin
on Fri Dec 15 15:41:58 GMT 2023
Record UNII
623D3XG80C
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
METHYL GALLATE
Systematic Name English
METHYL 3,4,5-TRIHYDROXYBENZOATE
Systematic Name English
BENZOIC ACID, 3,4,5-TRIHYDROXY-, METHYL ESTER
Systematic Name English
GALLIC ACID METHYL ESTER
MI  
Systematic Name English
GALLIC ACID METHYL ESTER [MI]
Common Name English
M G
Common Name English
NSC-363001
Code English
Code System Code Type Description
EPA CompTox
DTXSID3059189
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
WIKIPEDIA
METHYL GALLATE
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
ECHA (EC/EINECS)
202-741-7
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
PUBCHEM
7428
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
CAS
99-24-1
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
MERCK INDEX
m5645
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY Merck Index
FDA UNII
623D3XG80C
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
NSC
363001
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
CHEBI
145828
Created by admin on Fri Dec 15 15:41:58 GMT 2023 , Edited by admin on Fri Dec 15 15:41:58 GMT 2023
PRIMARY
Related Record Type Details
PARENT -> CONSTITUENT ALWAYS PRESENT
Methyl gallate exhibited a significant free radical scavenging effect against 1,1-diphenyl-2-picryl hydrazine (DPPH) radical generation and had an inhibitory effect on lipid peroxidation, as measured by the level of malondialdehyde (MDA) formation.
PARENT -> CONSTITUENT ALWAYS PRESENT
MIC 160 mg/L for ATCC 700392 and ATCC 700824 strains of H. pylori.