Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.971 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC=C2OC3=C(OC2=C1Cl)C=C(Cl)C(Cl)=C3
InChI
InChIKey=YDZCLBKUTXYYKS-UHFFFAOYSA-N
InChI=1S/C12H4Cl4O2/c13-5-1-2-8-12(11(5)16)18-10-4-7(15)6(14)3-9(10)17-8/h1-4H
| Molecular Formula | C12H4Cl4O2 |
| Molecular Weight | 321.971 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Resveratrol enhances NK cell cytotoxicity: possible role for aryl hydrocarbon receptor. | 2010-11 |
|
| Toxic effects of lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on development of male reproductive system: involvement of antioxidants, oxidants, and p53 protein. | 2010-02 |
|
| Re: False-positive results in cancer epidemiology: a plea for epistemological modesty. | 2010-01-20 |
|
| The effect of TCDD dioxin on the rat liver in biochemical and histological assessment. | 2010 |
|
| The role of aryl hydrocarbon receptor in regulation of enzymes involved in metabolic activation of polycyclic aromatic hydrocarbons in a model of rat liver progenitor cells. | 2009-07-15 |
|
| Transgenic mouse lines expressing rat AH receptor variants--a new animal model for research on AH receptor function and dioxin toxicity mechanisms. | 2009-04-15 |
|
| The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the mortality and growth of two amphibian species (Xenopus laevis and Pseudacris triseriata). | 2008-12 |
|
| High potency of bioactivation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mouse colon epithelial cells with Apc(Min) mutation. | 2008-05-31 |
|
| Pesticides, soft-tissue sarcoma and non-Hodgkin lymphoma--historical aspects on the precautionary principle in cancer prevention. | 2008 |
|
| Pesticides, soft tissue sarcoma and non-Hodgkin lymphoma. | 2008 |
|
| Glucocorticoid receptor functions in HeLa Cells are perturbed by 2,3,8,9-tetrachlorodibenzo-p-dioxin (TCDD). | 2007-12 |
|
| Constitutive expression and inducibility of CYP1A1 in the H9c2 rat cardiomyoblast cells. | 2007-12 |
|
| Cyclooxygenase-2 promoter activation by the aromatic hydrocarbon receptor in breast cancer mcf-7 cells: repressive effects of conjugated linoleic acid. | 2007 |
|
| Fate and transport of 1278-TCDD, 1378-TCDD, and 1478-TCDD in soil-water systems. | 2006-12-01 |
|
| Cytotoxicity of sanguinarine in primary rat hepatocytes is attenuated by dioxin and phenobarbital. | 2006-09-10 |
|
| Role of the carboxy-terminal transactivation domain and active transcription in the ligand-induced and ligand-independent degradation of the mouse Ahb-1 receptor. | 2005-11-25 |
|
| Activation of the aryl hydrocarbon receptor increases pulmonary neutrophilia and diminishes host resistance to influenza A virus. | 2005-07 |
|
| Detection of interaction of binding affinity of aromatic hydrocarbon receptor to the specific DNA by exonuclease protection mediated PCR assay. | 2005 |
|
| Activation of mitogen-activated protein kinases (MAPKs) by aromatic hydrocarbons: role in the regulation of aryl hydrocarbon receptor (AHR) function. | 2002-09 |
|
| cDNA cloning and characterization of an aryl hydrocarbon receptor from the harbor seal (Phoca vitulina): a biomarker of dioxin susceptibility? | 2002-07 |
|
| Metabolism of [14C]1,2,7,8-tetrachlorodibenzo-p-dioxin in a ruminating Holstein calf. | 2001-07 |
|
| Tissue distribution, excretion, and metabolism of 1,2,7,8-tetrachlorodibenzo-p-dioxin in the rat. | 2001-03 |
|
| Cloning and characterization of cDNAs encoding mouse Ugt1.6 and rabbit UGT1.6: differential induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | 1994-08-30 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:39:56 GMT 2025
by
admin
on
Mon Mar 31 19:39:56 GMT 2025
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| Record UNII |
61CLS478M1
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID3073478
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34816-53-0
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C445379
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61CLS478M1
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36934
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admin on Mon Mar 31 19:39:56 GMT 2025 , Edited by admin on Mon Mar 31 19:39:56 GMT 2025
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