CERIC OXIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	Ce.2O
Molecular Weight	172.115
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[O--].[O--].[Ce+4]

InChI

InChIKey=OFJATJUUUCAKMK-UHFFFAOYSA-N

InChI=1S/Ce.2O/q+4;2*-2

HIDE SMILES / InChI

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Ce
Molecular Weight	140.116
Charge	4
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Antioxidant and anti-genotoxic properties of cerium oxide nanoparticles in a pulmonary-like cell system.	2016-02	25618551
Cyto- and genotoxic effects of metallic nanoparticles in untransformed human fibroblast.	2015-10	26028148
Gene expression profiles reveal distinct immunological responses of cobalt and cerium dioxide nanoparticles in two in vitro lung epithelial cell models.	2014-08-04	24821434
TiO2, CeO2 and ZnO nanoparticles and modulation of the degranulation process in human neutrophils.	2013-07-31	23726862
Cerium oxide nanoparticles induce cytotoxicity in human hepatoma SMMC-7721 cells via oxidative stress and the activation of MAPK signaling pathways.	2013-04	23416263
Cerium dioxide nanoparticles can interfere with the associated cellular mechanistic response to diesel exhaust exposure.	2012-10-17	22960666
Distribution, elimination, and biopersistence to 90 days of a systemically introduced 30 nm ceria-engineered nanomaterial in rats.	2012-05	22367688
Zeta potential and solubility to toxic ions as mechanisms of lung inflammation caused by metal/metal oxide nanoparticles.	2012-04	22240982
Acute inhalation toxicity of cerium oxide nanoparticles in rats.	2011-08-28	21624445
Intratracheal instillation of cerium oxide nanoparticles induces hepatic toxicity in male Sprague-Dawley rats.	2011	22072870
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing.	2010-12	20729176
Brain distribution and toxicological evaluation of a systemically delivered engineered nanoscale ceria.	2010-08	20457660
Oxidative stress of CeO2 nanoparticles via p38-Nrf-2 signaling pathway in human bronchial epithelial cell, Beas-2B.	2009-06-01	19429248
Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation.	2009-02	19270794

Patents

Substance Class	Chemical Created by `admin` on `Wed Apr 02 18:00:09 GMT 2025` Edited by `admin` on `Wed Apr 02 18:00:09 GMT 2025`
Record UNII	619G5K328Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CERIUM OXIDE

Preferred Name

English

CERIC OXIDE

Common Name

English

CERIUM(IV) OXIDE

Common Name

English

CERIC OXIDE [MI]

Common Name

English

CERIA

Common Name

English

CERIUM DIOXIDE

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

731920