Sonpiretigene Isteparvovec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 19:53:41 UTC 2023` Edited by `admin` on `Sat Dec 16 19:53:41 UTC 2023`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependoparvovirus
Organism Species	adeno-associated dependoparvovirus a
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	AAV2-CMV-mGluR6 enhancer-MCO-010
Part	WHOLE
Record UNII	5Z6Q4P5ET5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Sonpiretigene Isteparvovec

Official Name

English

sonpiretigene isteparvovec [INN]

Common Name

English

recombinant, non-replicating adeno-associated virus serotype 2 (AAV2) vector, encoding a codon-optimized Chlamydomonas-derived ambient light-activatable multi-characteristic opsin (MCO) fusion protein with a Discosoma red fluorescent bioluminescence repo

Common Name

English

DNA (recombinant adeno-associated virus 2 vector vMCO-010 human cytomegalovirus promoter plus human metabotropic glutamate receptor mGluR6 enhancer plus Chlamydomonas opsin fusion with Discosoma red fluorescent protein mcherry codon-optimized transgene p

Common Name

English

Code System Code Type Description

FDA UNII

5Z6Q4P5ET5

Created by admin on Sat Dec 16 19:53:41 UTC 2023 , Edited by admin on Sat Dec 16 19:53:41 UTC 2023

PRIMARY

NCI_THESAURUS

C199113

Created by admin on Sat Dec 16 19:53:41 UTC 2023 , Edited by admin on Sat Dec 16 19:53:41 UTC 2023

PRIMARY

CAS

2658561-40-9

Created by admin on Sat Dec 16 19:53:41 UTC 2023 , Edited by admin on Sat Dec 16 19:53:41 UTC 2023

PRIMARY

INN

12405

Created by admin on Sat Dec 16 19:53:41 UTC 2023 , Edited by admin on Sat Dec 16 19:53:41 UTC 2023

PRIMARY

Related Record Type Details


					BRF2KG98RR

Sonpiretigene isteparvovec expressed protein

EXPRESSED PROTEIN->VECTOR

Amount:

Related Record Type Details


					5Z6Q4P5ET5

Sonpiretigene Isteparvovec

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					Sonpiretigene isteparvovec transgene insert	HMD24WK9S3