ZALUNFIBAN

NCC(=O)NC1=CN=CC(=C1)C2=NN3C(S2)=NC(=CC3=O)N4CCNCC4

InChIKey=LTVKZVGAALCRFW-UHFFFAOYSA-N

InChI=1S/C16H18N8O2S/c17-7-13(25)20-11-5-10(8-19-9-11)15-22-24-14(26)6-12(21-16(24)27-15)23-3-1-18-2-4-23/h5-6,8-9,18H,1-4,7,17H2,(H,20,25)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
platelet aggregation 76 Target ID: GO:0070527 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24461295 \| https://www.ncbi.nlm.nih.gov/pubmed/25147334	Inhibitor 8297		45.0 nM [IC50]
Integrin alpha-IIb/beta-3 14 Target ID: CHEMBL2093869 Sources: https://www.ncbi.nlm.nih.gov/pubmed/24461295 \| https://www.ncbi.nlm.nih.gov/pubmed/25147334	Antagonist 2778

Substance Class	Chemical Created by `admin` on `Sat Dec 16 14:25:37 GMT 2023` Edited by `admin` on `Sat Dec 16 14:25:37 GMT 2023`
Record UNII	5XQC91CO1F
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

ZALUNFIBAN

Official Name

English

ZALUNFIBAN [USAN]

Common Name

English

ACETAMIDE, 2-AMINO-N-(5-(5-OXO-7-(1-PIPERAZINYL)-5H-1,3,4-THIADIAZOLO(3,2- A)PYRIMIDIN-2-YL)-3-PYRIDINYL)-

Systematic Name

English

RUC-4

Code

English

zalunfiban [INN]

Common Name

English

RUC4

Code

English

2-AMINO-N-(4-(5-OXO-7-(PIPERAZIN-1-YL)-5H-(1,3,4)THIADIAZOLO(3,2-A)PYRIMIDIN-2-YL)PYRIDIN-2-YL)ACETAMIDE

Systematic Name

English

Code System Code Type Description

USAN

HI-59