U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:23:14 GMT 2023
Edited
by admin
on Sat Dec 16 14:23:14 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
5XO3JF0FEK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VIBOSTOLIMAB
USAN   INN  
Official Name English
MK-7684
Preferred Name English
TIGIT INHIBITOR MK-7684
Code English
Vibostolimab [WHO-DD]
Common Name English
VIBOSTOLIMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN RECEPTOR TIGIT (T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS)) (HUMAN-MUS MUSCULUS MONOCLONAL C011 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL C011 .KAPPA.-CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS, V-SET AND IMMUNOGLOBULIN DOMAIN-CONTAINING PROTEIN 9, V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN 3)HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN HUMANI
Common Name English
MK-7684A COMPONENT VIBOSTOLIMAB
Common Name English
TIGIT-TARGETING AGENT MK-7684
Code English
MK7684
Code English
vibostolimab [INN]
Common Name English
T-CELL IMMUNOGLOBULIN AND IMMUNORECEPTOR TYROSINE-BASED INHIBITORY MOTIF INHIBITOR MK-7684
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C141144
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
FDA ORPHAN DRUG 893722
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
NCI_THESAURUS C129820
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
Code System Code Type Description
CAS
2231305-30-7
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
PRIMARY
USAN
FG-215
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
PRIMARY
FDA UNII
5XO3JF0FEK
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
PRIMARY
INN
11178
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
PRIMARY
NCI_THESAURUS
C140041
Created by admin on Sat Dec 16 14:23:14 GMT 2023 , Edited by admin on Sat Dec 16 14:23:14 GMT 2023
PRIMARY
From To
1_22 1_96
2_22 2_96
2_146 2_202
2_222 4_214
2_263 2_323
1_146 1_202
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_222 3_214
1_228 2_228
1_231 2_231
1_263 1_323
1_369 1_427
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_299
N 2_299
Related Record Type Details
TARGET -> INHIBITOR
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL