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Details

Stereochemistry ACHIRAL
Molecular Formula C4H8
Molecular Weight 56.1063
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCLOBUTANE

SMILES

C1CCC1

InChI

InChIKey=PMPVIKIVABFJJI-UHFFFAOYSA-N
InChI=1S/C4H8/c1-2-4-3-1/h1-4H2

HIDE SMILES / InChI

Molecular Formula C4H8
Molecular Weight 56.1063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
The XPC poly-AT polymorphism in non-melanoma skin cancer.
2005-05-26
Intramolecular hydroarylation of alkynes catalyzed by platinum or gold: mechanism and endo selectivity.
2005-05-06
Time-resolved study of thymine dimer formation.
2005-04-27
Ultraviolet radiation-mediated damage to cellular DNA.
2005-04-01
Cyclobutane dimers from the Colombian medicinal plant Achyrocline bogotensis.
2005-04
Generation and reactions of two new functionalized tricyclo[3.3.0.0 3,7]oct-1(5)-ene derivatives.
2005-03-04
Synthesis and complexing properties of [2.n](2,6)pyridinocrownophanes.
2005-03-04
Nigramides A-S, dimeric amide alkaloids from the roots of Piper nigrum.
2005-02-18
Continuity in symmetry and in distinguishability of states: the symmetry numbers of nonrigid molecules.
2005-02-15
Formation of a bridging planar trimethylenemethane dianion from a neopentyl precursor via sequential beta-alkyl elimination and C-H activation.
2005-02-02
The relative roles in vivo of Saccharomyces cerevisiae Pol eta, Pol zeta, Rev1 protein and Pol32 in the bypass and mutation induction of an abasic site, T-T (6-4) photoadduct and T-T cis-syn cyclobutane dimer.
2005-02
Intramolecular photocycloaddition of dioxenones with alkynes: formation of secondary photoproducts from cyclobutene photoadducts.
2005-01-20
Synthesis of cyclobutane serine analogues.
2005-01-07
Recognition and processing of cisplatin- and oxaliplatin-DNA adducts.
2005-01
The cryptochromes.
2005
[Raman spectroscopy study of 1,3-dimethyluracil and its ab initio (DFT) calculation].
2004-12
Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells.
2004-11-22
New types of soluble polymer-supported bisphosphine ligands with a cyclobutane backbone for Pd-catalyzed enantioselective allylic substitution reactions.
2004-11-19
Stereoselective Rh-catalyzed hydrogenation of cyclobutyl chiral enamides: double stereodifferentiation vs catalyst-controlled diastereoselection.
2004-11-12
The photochemistry of thymidylyl-(3'-5')-5-methyl-2'-deoxycytidine in aqueous solution.
2004-10-21
Dissociative electron transfer to and from pyrimidine cyclobutane dimers: an electrochemical study.
2004-10-07
The cyclobutane dimers of 5-methylcytosine and their deamination products.
2004-10
Protein interactions with platinum-DNA adducts: from structure to function.
2004-10
1-Methyl-1-phenyl-3-[1-hydroxyimino-2-(succinimido)ethyl]cyclobutane.
2004-09
Palladium-catalyzed transformation of cyclobutanone O-benzoyloximes to nitriles via C-C bond cleavage.
2004-08-06
14-helical folding in a cyclobutane-containing beta-tetrapeptide.
2004-07-23
(Benzofuran-2-yl)(3-methyl-3-phenylcyclobutyl)methanone.
2004-07
Entamoeba histolytica alcohol dehydrogenase 2 (EhADH2) as a target for anti-amoebic agents.
2004-07
Copper(I)-catalyzed intramolecular asymmetric [2 + 2] photocycloaddition. Synthesis of both enantiomers of cyclobutane derivatives.
2004-06-10
Multigram-scale syntheses, stability, and photoreactions of A2A adenosine receptor antagonists with 8-styrylxanthine structure: potential drugs for Parkinson's disease.
2004-05-14
Strain energy of small ring hydrocarbons. Influence of C-h bond dissociation energies.
2004-04-07
Unusual intramolecular [2 + 2] cycloaddition of allyl and vinylidene C=C bonds under mild conditions: a theoretical analysis.
2004-04-02
Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts.
2004-02
Catalytic (2 + 2)-cycloaddition reactions of silyl enol ethers. A convenient and stereoselective method for cyclobutane ring formation.
2004-01-23
A computational investigation of the reactions of methylene, chlorocarbene, and dichlorocarbene with cyclopropane.
2004-01-23
[Development of novel carbon-carbon bond forming reactions using zirconocene complex].
2003-11
Conformational restraint in thermal rearrangements of a cyclobutane: 3,4-dicyanotricyclo[4.2.2.0(2,5)]decane.
2003-09-03
Translesion replication in cisplatin-treated xeroderma pigmentosum variant cells is also caffeine-sensitive: features of the error-prone DNA polymerase(s) involved in UV-mutagenesis.
2003-08-12
Toward tissue-selective pancreatic B-cells KATP channel openers belonging to 3-alkylamino-7-halo-4H-1,2,4-benzothiadiazine 1,1-dioxides.
2003-07-17
A new type of C2-symmetric bisphospine ligands with a cyclobutane backbone: practical synthesis and application.
2003-04-17
Formation of the spore photoproduct and other dimeric lesions between adjacent pyrimidines in UVC-irradiated dry DNA.
2003-04
The application of cyclobutane derivatives in organic synthesis.
2003-04
Enantiomerically pure cyclobutane derivatives and their use in organic synthesis.
2003-04
Acid-catalyzed Grob fragmentation reactions of acetonides derived from terpenes.
2003-03-20
Formation of a cyclobutylidene ring: intramolecular [2 + 2] cycloaddition of allyl and vinylidene C=C bonds under mild conditions.
2003-03-05
Truxillic and truxinic acids--occurrence in plant kingdom.
2003-02-27
DNA damage and alterations of gene expression in chronic-degenerative diseases.
2003
Formation of 2'-deoxyuridine hydrates upon exposure of nucleosides to gamma radiation and UVC-irradiation of isolated and cellular DNA.
2002-08
UV-absorbing substance in the red alga Porphyra yezoensis (Bangiales, Rhodophyta) block thymine photodimer production.
2001-08-16
Resolution of UV-induced DNA damage in Xiphophorus fishes.
2001-06
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:56:57 GMT 2025
Edited
by admin
on Mon Mar 31 19:56:57 GMT 2025
Record UNII
5X619RB2CY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYCLOBUTANE [HSDB]
Preferred Name English
CYCLOBUTANE
HSDB   MI  
Systematic Name English
CYCLOBUTANE [MI]
Common Name English
TETRAMETHYLENE
Common Name English
Code System Code Type Description
CHEBI
30377
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
CHEBI
30963
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
ECHA (EC/EINECS)
206-014-5
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
HSDB
58
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
FDA UNII
5X619RB2CY
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
PUBCHEM
9250
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
MERCK INDEX
m3978
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY Merck Index
EPA CompTox
DTXSID2059772
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
WIKIPEDIA
CYCLOBUTANE
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY
CAS
287-23-0
Created by admin on Mon Mar 31 19:56:57 GMT 2025 , Edited by admin on Mon Mar 31 19:56:57 GMT 2025
PRIMARY