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Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 20:01:00 GMT 2023
Edited
by admin
on Sat Dec 16 20:01:00 GMT 2023
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED
Sequence Type COMPLETE
Record UNII
5W7SK85BMU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Cabotamig
INN  
Official Name English
cabotamig [INN]
Common Name English
Immunoglobulin G4, anti-(human cadherin 17) (human-Mus musculus hybrid γ1/γ4-chain precursor) fusion protein with peptide linker (PAGGGGS) fusion protein with immunoglobulin anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment
Common Name English
VH-G1CH1h-G4CH2CH3-scFv fused heavy chain humanized (1-697) [VH-G1CH1h-G4CH2CH3 heavy chain anti-CDH17 humanized (1-446) [(VH(Homo sapiens IGHV3-23*04 (89.7%) -(IGHD) -IGHJ4*01 (91.7%) S128>A(116), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116)-Homo sapi
Common Name English
Immunoglobulin VH-G1CH1h-G4CH2CH3-scFv_L-kappa dimer, anti-[Homo sapiens CDH17 (cadherin 17)], anti-[Homo sapiens CD3E (CD3epsilon, Leu-4)], monoclonal antibody humanized, bispecific
Common Name English
Code System Code Type Description
INN
12632
Created by admin on Sat Dec 16 20:01:00 GMT 2023 , Edited by admin on Sat Dec 16 20:01:00 GMT 2023
PRIMARY
FDA UNII
5W7SK85BMU
Created by admin on Sat Dec 16 20:01:00 GMT 2023 , Edited by admin on Sat Dec 16 20:01:00 GMT 2023
PRIMARY
CAS
2755301-09-6
Created by admin on Sat Dec 16 20:01:00 GMT 2023 , Edited by admin on Sat Dec 16 20:01:00 GMT 2023
PRIMARY
From To
1_228 2_228
1_225 2_225
2_219 4_214
1_219 3_214
4_134 4_194
4_23 4_88
3_134 3_194
3_23 3_88
1_613 1_678
2_613 2_678
1_475 1_549
2_475 2_549
1_366 1_424
2_366 2_424
1_260 1_320
2_260 2_320
1_143 1_199
2_143 2_199
1_22 1_96
2_22 2_96
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
TARGET -> ACTIVATOR
TARGET->LIGAND
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL