Cabotamig

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 20:01:00 UTC 2023` Edited by `admin` on `Sat Dec 16 20:01:00 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	5W7SK85BMU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cabotamig

Official Name

English

cabotamig [INN]

Common Name

English

Immunoglobulin G4, anti-(human cadherin 17) (human-Mus musculus hybrid γ1/γ4-chain precursor) fusion protein with peptide linker (PAGGGGS) fusion protein with immunoglobulin anti-(human CD3 antigen ε-chain) (human-Mus musculus single-chain Fv fragment

Common Name

English

VH-G1CH1h-G4CH2CH3-scFv fused heavy chain humanized (1-697) [VH-G1CH1h-G4CH2CH3 heavy chain anti-CDH17 humanized (1-446) [(VH(Homo sapiens IGHV3-23*04 (89.7%) -(IGHD) -IGHJ4*01 (91.7%) S128>A(116), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116)-Homo sapi

Common Name

English

Immunoglobulin VH-G1CH1h-G4CH2CH3-scFv_L-kappa dimer, anti-[Homo sapiens CDH17 (cadherin 17)], anti-[Homo sapiens CD3E (CD3epsilon, Leu-4)], monoclonal antibody humanized, bispecific

Common Name

English

Code System Code Type Description

INN

12632

Created by admin on Sat Dec 16 20:01:00 UTC 2023 , Edited by admin on Sat Dec 16 20:01:00 UTC 2023

PRIMARY

FDA UNII

5W7SK85BMU

Created by admin on Sat Dec 16 20:01:00 UTC 2023 , Edited by admin on Sat Dec 16 20:01:00 UTC 2023

PRIMARY

CAS

2755301-09-6

Created by admin on Sat Dec 16 20:01:00 UTC 2023 , Edited by admin on Sat Dec 16 20:01:00 UTC 2023

PRIMARY

From	To
1_228	2_228
1_225	2_225
2_219	4_214
1_219	3_214
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
1_613	1_678
2_613	2_678
1_475	1_549
2_475	2_549
1_366	1_424
2_366	2_424
1_260	1_320
2_260	2_320
1_143	1_199
2_143	2_199
1_22	1_96
2_22	2_96