Cabotamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 18:04:30 GMT 2025` Edited by `admin` on `Wed Apr 02 18:04:30 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	5W7SK85BMU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Cabotamig

Official Name

English

Immunoglobulin G4, anti-(human cadherin 17) (human-Mus musculus hybrid ?1/?4-chain precursor) fusion protein with peptide linker (PAGGGGS) fusion protein with immunoglobulin anti-(human CD3 antigen ?-chain) (human-Mus musculus single-chain Fv fragment VH

Preferred Name

English

cabotamig [INN]

Common Name

English

VH-G1CH1h-G4CH2CH3-scFv fused heavy chain humanized (1-697) [VH-G1CH1h-G4CH2CH3 heavy chain anti-CDH17 humanized (1-446) [(VH(Homo sapiens IGHV3-23*04 (89.7%) -(IGHD) -IGHJ4*01 (91.7%) S128>A(116), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116)-Homo sapi

Common Name

English

Immunoglobulin VH-G1CH1h-G4CH2CH3-scFv_L-kappa dimer, anti-[Homo sapiens CDH17 (cadherin 17)], anti-[Homo sapiens CD3E (CD3epsilon, Leu-4)], monoclonal antibody humanized, bispecific

Common Name

English

Code System Code Type Description

INN

12632