U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 17:56:50 GMT 2023
Edited
by admin
on Sat Dec 16 17:56:50 GMT 2023
Nucleic Acid Type VECTOR
Nucleic Acid Subtype TRANSGENE
Sequence Type COMPLETE
Record UNII
5VHE3TN4GY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PLIXACABTAGENE AUTOLEUCEL TRANSGENE INSERT
Common Name English
PLIXACABTAGENE AUTOLEUCEL TRANSGENE INSERT ENCODING A CHIMERIC ANTIGEN RECEPTOR (CAR) TARGETING CD19
Common Name English
Code System Code Type Description
FDA UNII
5VHE3TN4GY
Created by admin on Sat Dec 16 17:56:50 GMT 2023 , Edited by admin on Sat Dec 16 17:56:50 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_1-1_5122 5122 / 5122
Linkage Site Range Site Count
Phosphate 1_2-1_5122 5121 / 5121
Name Property Type Amount Referenced Substance Defining Parameters References
chimeric antigen receptor (CAR) targeting CD19 NUCLEIC ACID FEATURE
HIV 3’ polypurine tract (PPT) region NUCLEIC ACID FEATURE
HIV-1 PSI packaging signal NUCLEIC ACID FEATURE
Optimized Woodchuck hepatitis virus Posttranscriptional Regulatory Element (PRE) NUCLEIC ACID FEATURE
Truncated gag NUCLEIC ACID FEATURE
3’ Long Terminal Repeat (LTR) NUCLEIC ACID FEATURE
Extended Rev response element NUCLEIC ACID FEATURE
Primer binding site NUCLEIC ACID FEATURE
EF-1a Promotor NUCLEIC ACID FEATURE
5’ Long Terminal Repeat (LTR) NUCLEIC ACID FEATURE