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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6O3.C4H11N
Molecular Weight 211.258
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIETHYLAMINE SALICYLATE

SMILES

c1ccc(c(c1)C(=O)O)O.CCNCC

InChI

InChIKey=JGMKRAUEFASZKH-UHFFFAOYSA-N
InChI=1S/C7H6O3.C4H11N/c8-6-4-2-1-3-5(6)7(9)10;1-3-5-4-2/h1-4,8H,(H,9,10);5H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C4H11N
Molecular Weight 73.137
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H6O3
Molecular Weight 138.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment:: https://www.ncbi.nlm.nih.gov/pubmed/14757512 | https://www.ncbi.nlm.nih.gov/pubmed/12356424

Diethylamine salicylate is a salicylic acid salt, that is a cost-effective and simple, first-line treatment for rheumatic and minor musculoskeletal conditions including lumbago, fibrositis, sciatica, bruises, and strains. Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.

Originator

Sources: Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales, Volume 142, Pages 819-21, Journal, 1948

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Algesal
Sourcing
PubMed

PubMed

TitleDatePubMed
Differentiated in vivo skin penetration of salicylic compounds in hairless rats measured by cutaneous microdialysis.
2004 Feb
Patents

Patents

Sample Use Guides

Topical As 10% cream: Apply 2-3 times/day.
Route of Administration: Topical
Substance Class Chemical
Created
by admin
on Sat Jun 26 10:28:55 UTC 2021
Edited
by admin
on Sat Jun 26 10:28:55 UTC 2021
Record UNII
5V7PT38BJU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIETHYLAMINE SALICYLATE
MART.   WHO-DD  
Systematic Name English
DIETHYLAMINE SALICYLATE [MART.]
Common Name English
DIETHYLAMMONIUM SALICYLATE
Systematic Name English
DIETHYLAMINE SALICYLATE [WHO-DD]
Common Name English
Code System Code Type Description
CAS
4419-92-5
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
RXCUI
162592
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY RxNorm
EVMPD
SUB13573MIG
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
ECHA (EC/EINECS)
224-586-4
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
MESH
C026191
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
PUBCHEM
9837223
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
FDA UNII
5V7PT38BJU
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE