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Details

Stereochemistry ACHIRAL
Molecular Formula C7H6O3.C4H11N
Molecular Weight 211.258
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIETHYLAMINE SALICYLATE

SMILES

c1ccc(c(c1)C(=O)O)O.CCNCC

InChI

InChIKey=JGMKRAUEFASZKH-UHFFFAOYSA-N
InChI=1S/C7H6O3.C4H11N/c8-6-4-2-1-3-5(6)7(9)10;1-3-5-4-2/h1-4,8H,(H,9,10);5H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C4H11N
Molecular Weight 73.137
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C7H6O3
Molecular Weight 138.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment:: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/pubmed/14757512 | https://www.ncbi.nlm.nih.gov/pubmed/12356424

Diethylamine salicylate is a salicylic acid salt, that is a cost-effective and simple, first-line treatment for rheumatic and minor musculoskeletal conditions including lumbago, fibrositis, sciatica, bruises, and strains. Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (COX-1 and COX-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms.

Originator

Sources: Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales, Volume 142, Pages 819-21, Journal, 1948

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Algesal

Approved Use

Unknown
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
Differentiated in vivo skin penetration of salicylic compounds in hairless rats measured by cutaneous microdialysis.
2004 Feb
Patents

Patents

Sample Use Guides

Topical As 10% cream: Apply 2-3 times/day.
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Jun 26 10:28:55 UTC 2021
Edited
by admin
on Sat Jun 26 10:28:55 UTC 2021
Record UNII
5V7PT38BJU
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIETHYLAMINE SALICYLATE
MART.   WHO-DD  
Systematic Name English
DIETHYLAMINE SALICYLATE [MART.]
Common Name English
DIETHYLAMMONIUM SALICYLATE
Systematic Name English
DIETHYLAMINE SALICYLATE [WHO-DD]
Common Name English
Code System Code Type Description
CAS
4419-92-5
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
RXCUI
162592
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY RxNorm
EVMPD
SUB13573MIG
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
ECHA (EC/EINECS)
224-586-4
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
MESH
C026191
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
PUBCHEM
9837223
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
FDA UNII
5V7PT38BJU
Created by admin on Sat Jun 26 10:28:55 UTC 2021 , Edited by admin on Sat Jun 26 10:28:55 UTC 2021
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE