Tesrivetcel

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Sat Dec 16 19:58:08 GMT 2023` Edited by `admin` on `Sat Dec 16 19:58:08 GMT 2023`
Source Materials Class	ORGANISM
Source Materials Type	MAMMAL
Source Materials Parent	`R7AD7Y06PL` EQUUS CABALLUS WHOLE
Part	BLOOD
Fraction Name	Peripheral blood mononuclear cells (PBMCs)
Record UNII	5V2WV5E8ZJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Tesrivetcel

Official Name

English

equine allogeneic tenogenic-primed mesenchymal stromal/stem cells (MSCs), isolated from peripheral blood mononuclear cells (PBMCs) collected from donor horses. The MSCs are selected for by growing the PBMCs in media containing fetal bovine serum (FBS) an

Common Name

English

tesrivetcel [INN]

Common Name

English

Code System Code Type Description

FDA UNII

5V2WV5E8ZJ

Created by admin on Sat Dec 16 19:58:08 GMT 2023 , Edited by admin on Sat Dec 16 19:58:08 GMT 2023

PRIMARY

INN

12665

Created by admin on Sat Dec 16 19:58:08 GMT 2023 , Edited by admin on Sat Dec 16 19:58:08 GMT 2023

PRIMARY

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CARTILAGE OLIGOMERIC MATRIX PROTEIN

CONSTITUENT ALWAYS PRESENT -> PARENT

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					5V2WV5E8ZJ

Tesrivetcel

ACTIVE MOIETY

Comments:

Differentiation towards tenocytes, cell therapy (veterinary use)

Amount:

Agent Modifications

Modification Process	Modification Role	Modification Type	Fragment Name	Fragment ID
CULTURE	EXPANSION	BIOLOGICAL	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	Mesenchymal stromal/stem cells (MSCs) selection	CELL SEPARATION	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	DIFFERENTIATION AGENT	DIFFERENTIATION	BASIC FIBROBLAST GROWTH FACTOR (HUMAN)	S3529G9M9V
CULTURE	DIFFERENTIATION AGENT	DIFFERENTIATION	MECASERMIN	7GR9I2683O
CULTURE		DIFFERENTION	FETAL SERUM, BOVINE	K5DD3J879P
CULTURE	Mesenchymal stromal/stem cells (MSCs) selection	CELL SEPARATION	DEXAMETHASONE	7S5I7G3JQL

Name	Property Type	Referenced Substance
ANTIGEN EXPRESSED	BIOLOGICAL	`EAD36Y912K` THY-1 MEMBRANE GLYCOPROTEIN

ANTIGEN EXPRESSED	BIOLOGICAL	`CA9PO31PIJ` TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5