Bosakitug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 17:26:58 GMT 2025` Edited by `admin` on `Wed Apr 02 17:26:58 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	5T953J9HZN
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Bosakitug

Official Name

English

BSI-045B

Preferred Name

English

Immunoglobulin G1, anti-(human thymic stromal lymphopoietin) (human-Mus musculus monoclonal BSI-045B ?1-chain), disulfide with human-Mus musculus monoclonal BSI-045B ?-chain, dimer

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens TSLP (thymic stromal lymphopoietin)], humanized monoclonal antibody; H-gamma1 heavy chain humanized (1-447) [VH (Homo sapiens IGHV1-46*01 (88.8%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.10] (26-33.51-58.97-106

Common Name

English

bosakitug [INN]

Common Name

English

Code System Code Type Description

FDA UNII

5T953J9HZN

Created by admin on Wed Apr 02 17:26:58 GMT 2025 , Edited by admin on Wed Apr 02 17:26:58 GMT 2025

PRIMARY

SMS_ID

300000054748

Created by admin on Wed Apr 02 17:26:58 GMT 2025 , Edited by admin on Wed Apr 02 17:26:58 GMT 2025

PRIMARY

NCI_THESAURUS

C206887

Created by admin on Wed Apr 02 17:26:58 GMT 2025 , Edited by admin on Wed Apr 02 17:26:58 GMT 2025

PRIMARY

CAS

2762183-23-1

Created by admin on Wed Apr 02 17:26:58 GMT 2025 , Edited by admin on Wed Apr 02 17:26:58 GMT 2025

PRIMARY

INN

12985

Created by admin on Wed Apr 02 17:26:58 GMT 2025 , Edited by admin on Wed Apr 02 17:26:58 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_144	2_200
2_220	4_214
2_261	2_321
1_144	1_200
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_220	3_214
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					GT0IL38SP4

THYMIC STROMAL LYMPHOPOIETIN

TARGET->LIGAND

Amount:

Related Record Type Details


					5T953J9HZN

Bosakitug

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL