Bulumtatug

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 16:45:00 GMT 2025` Edited by `admin` on `Wed Apr 02 16:45:00 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	5SR4N8C6KP
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Bulumtatug

Official Name

English

H-gamma1 heavy chain (1-449) [VH Musmus/Homsap (Mus musculus IGHV2-6-5*01 (78.4%) -(IGHD) -IGHJ3*01 (91.7%) A128>S (119)/Homo sapiens IGHV4-4*08 (78.4%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.13] (26-33.51-57.96-108)) (1-119) -Homo sapiens IGHG1*03 (100

Preferred Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens NECTIN4 (nectin-4, nectin cell adhesion molecule 4, PVRL4, poliovirus receptor-related 4, PPR4, LNIR)]

Common Name

English

bulumtatug [INN]

Common Name

English

Code System Code Type Description

FDA UNII

5SR4N8C6KP

Created by admin on Wed Apr 02 16:45:00 GMT 2025 , Edited by admin on Wed Apr 02 16:45:00 GMT 2025

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SMS_ID

300000054188

Created by admin on Wed Apr 02 16:45:00 GMT 2025 , Edited by admin on Wed Apr 02 16:45:00 GMT 2025

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INN

13082

Created by admin on Wed Apr 02 16:45:00 GMT 2025 , Edited by admin on Wed Apr 02 16:45:00 GMT 2025

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CAS

2862919-81-9

Created by admin on Wed Apr 02 16:45:00 GMT 2025 , Edited by admin on Wed Apr 02 16:45:00 GMT 2025

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NCI_THESAURUS

C211701

Created by admin on Wed Apr 02 16:45:00 GMT 2025 , Edited by admin on Wed Apr 02 16:45:00 GMT 2025

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From	To
1_22	1_95
2_22	2_95
2_146	2_202
2_222	4_220
2_263	2_323
1_146	1_202
2_369	2_427
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_222	3_220
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					2VLM5YIR4K

NECTIN-4

TARGET->LIGAND

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_449] [2_449]	C-TERMINUS		Amount:	LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL