BENZENEACETAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H9NO
Molecular Weight	135.1632
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(=O)CC1=CC=CC=C1

InChI

InChIKey=LSBDFXRDZJMBSC-UHFFFAOYSA-N

InChI=1S/C8H9NO/c9-8(10)6-7-4-2-1-3-5-7/h1-5H,6H2,(H2,9,10)

HIDE SMILES / InChI

Molecular Formula	C8H9NO
Molecular Weight	135.1632
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
LC-MS profiling of N-alkylamides in Spilanthes acmella extract and the transmucosal behaviour of its main bio-active spilanthol.	2010-11-02	20227845
2,3-Disubstituted acrylamides as potent glucokinase activators.	2010-10-01	20805029
Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: the basis of the genotype 1b vs. 3a inhibitor potency shift.	2010-09-30	20630554
Antitrypanosomal and antileishmanial activities of novel N-alkyl-(1-phenylsubstituted-beta-carboline)-3-carboxamides.	2010-07	20382497
Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives.	2010-04-01	20219371
The influence of leukotriene receptors' antagonists on experimentally induced ulcer in rats.	2010-03-06	20201264
Heterologous expression of leader-less pga gene in Pichia pastoris: intracellular production of prokaryotic enzyme.	2010-02-03	20128906
2-(4-Bromo-phen-yl)-N-(2-methoxy-phen-yl)acetamide.	2009-12-09	21580168
Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2.	2009-10-18	19835630
Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.	2009-07-15	19539481
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.	2009-06-15	19435663
N-(3,4-Diethoxy-phen-yl)acetamide.	2009-05-20	21583171
Utility of MetaSite in improving metabolic stability of the neutral indomethacin amide derivative and selective cyclooxygenase-2 inhibitor 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethyl-acetamide.	2009-05	19196840
Phenylethylamide and phenylmethylamide derivatives as new tyrosinase inhibitors.	2009-02	19182394
Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold.	2008-06-12	18473434
Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus.	2008-06	18491867
QSAR and pharmacophore analysis on amides against drug-resistant S. aureus.	2008-03-04	18311638
2,2-Dichloro-N-(2,3-dimethyl-phen-yl)acetamide.	2007-12-12	21200801
Production of enantiomerically pure (S)-beta-phenylalanine and (R)-beta-phenylalanine by penicillin G acylase from Escherichia coli in aqueous medium.	2007-12	17657412
Diastereospecific photocyclization of a isopropylbenzophenone derivative in crystals and the morphological changes.	2007-08-31	17691740
Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents.	2007-03-01	17223562
Fluorogenic substrates for lipases, esterases, and acylases using a TIM-mechanism for signal release.	2007-02	17219461
Synthesis and receptor binding studies of 3-substituted piperazine derivatives.	2006-03	16446011
[Studies on chemical constituents of the brown alga Dictyopteris divaricata].	2006-01	16570798
Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice.	2005-08-01	15950196
Metabolism of 2-phenylethylamine to phenylacetic acid, via the intermediate phenylacetaldehyde, by freshly prepared and cryopreserved guinea pig liver slices.	2005-01-14	15646820
SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease.	2004-09-06	15357995
Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.	2004-07-05	15177471
Mandelamide hydrolase from Pseudomonas putida: characterization of a new member of the amidase signature family.	2004-06-22	15196015
Studies on anti-Helicobacter pylori agents. Part 3: A novel, efficacious cephem derivative, FR193879.	2004-05-17	15109666
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.	2004-03-11	14998332
Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites.	2004-01	14709628
Bhimamycin A to approximately E and bhimanone: isolation, structure elucidation and biological activity of novel quinone antibiotics from a terrestrial Streptomycete.	2003-11	14763559
Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures.	2003-08-18	12873506
Design of selective peptidomimetic agonists for the human orphan receptor BRS-3.	2003-05-08	12723954
The scent of age.	2003-05-07	12803907
Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling.	2003-01-30	12540231
Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli.	2002-07-01	12071857
Synthesis and antimicrobial activity of some novel 2-(p-substituted-phenyl)-5-substituted-carbonylaminobenzoxazoles.	2002-03	11989794
Synthesis and structure-activity relationships of N-(1-benzylpiperidin-4-yl)arylacetamide analogues as potent sigma1 receptor ligands.	2001-12-06	11728186
A chemostat culture as a tool for the improvement of a recombinant E. coli strain over-producing penicillin G acylase.	2001-10-05	11536126
An enzyme-labile safety catch linker for synthesis on a soluble polymeric support.	2001-03-02	11303876
Substitutions of Thr-103-Ile and Trp-138-Gly in amidase from Pseudomonas aeruginosa are responsible for altered kinetic properties and enzyme instability.	2001-03	11434308
Potent and use-dependent block of cardiac sodium channels by U-50,488H, a benzeneacetamide kappa opioid receptor agonist.	2001	20428265
Isolation and characterization of a bacterium possessing a novel aldoxime-dehydration activity and nitrile-degrading enzymes.	1998-08	9683644

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:21:48 GMT 2025` Edited by `admin` on `Mon Mar 31 21:21:48 GMT 2025`
Record UNII	5R219M9TJF
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZENEACETAMIDE

Systematic Name

English

.ALPHA.-PHENYLACETAMIDE

Preferred Name

English

PHENACETAMIDE

Common Name

English

PHENYL-.BETA.-ACETYLAMINE

Common Name

English

PHENYLACETAMIDE

Common Name

English

PHENYLACETIC ACID AMIDE

Systematic Name

English

BENZENEDIACETAMIDE

Systematic Name

English

.ALPHA.-TOLUAMIDE

Systematic Name

English

NSC-1877

Code

English

.ALPHA.-TOLUIMIDIC ACID

Systematic Name

English

ACETAMIDE, 2-PHENYL-

Systematic Name

English

.ALPHA.-PHENYLACETAMIDE [MI]

Common Name

English

2-PHENYLACETAMIDE

Systematic Name

English

Code System Code Type Description

CAS

103-81-1