1,2,3,4,7,8-HEXACHLORODIBENZO-P-DIOXIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H2Cl6O2
Molecular Weight	390.861
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 1,2,3,4,7,8-HEXACHLORODIBENZO-P-DIOXIN

Structure Search

SMILES

ClC1=CC2=C(OC3=C(Cl)C(Cl)=C(Cl)C(Cl)=C3O2)C=C1Cl

InChI

InChIKey=WCYYQNSQJHPVMG-UHFFFAOYSA-N

InChI=1S/C12H2Cl6O2/c13-3-1-5-6(2-4(3)14)20-12-10(18)8(16)7(15)9(17)11(12)19-5/h1-2H

HIDE SMILES / InChI

Molecular Formula	C12H2Cl6O2
Molecular Weight	390.861
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Aryl hydrocarbon receptor (AHR)-regulated transcriptomic changes in rats sensitive or resistant to major dioxin toxicities.	2010-04-26	20420666
Bacterial degradation of aromatic compounds.	2009-01	19440284
Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats.	2007-06-03	17448584
Cell-free bioassay for measurement of dioxins based on fluorescence enhancement of fluorescein isothiocyanate-labeled DNA probe.	2006-10-15	17037913
Cytochrome P450 1A4 and 1A5 in common cormorant (Phalacrocorax carbo): evolutionary relationships and functional implications associated with dioxin and related compounds.	2006-08	16679348
Aryl hydrocarbon receptor (AHR) and AHR nuclear translocator (ARNT) expression in Baikal seal (Pusa sibirica) and association with 2,3,7,8-TCDD toxic equivalents and CYP1 expression levels.	2005-07	16111922
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin (HxCDD) alter body weight by decreasing insulin-like growth factor I (IGF-I) signaling.	2005-05	15703265
Evaluation of serum dioxin congeners among residents near continuously burning municipal solid waste incinerators in Korea.	2005-04	15744508
Effect of Chlorella pyrenoidosa on fecal excretion and liver accumulation of polychlorinated dibenzo-p-dioxin in mice.	2005-04	15722102
Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds.	2003-09	12850102
Half-lives of tetra-, penta-, hexa-, hepta-, and octachlorodibenzo-p-dioxin in rats, monkeys, and humans--a critical review.	2002-08	12143938
Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains.	2002-05-15	12030841
Relative potencies of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners to induce cytochrome P4501A mRNA in a zebrafish liver cell line.	2001-05	11337868

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:51:34 GMT 2025` Edited by `admin` on `Mon Mar 31 18:51:34 GMT 2025`
Record UNII	5R0UY33JFS
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,2,3,4,7,8-HXCDD

Preferred Name

English

1,2,3,4,7,8-HEXACHLORODIBENZO-P-DIOXIN

Common Name

English

DIBENZO(B,E)(1,4)DIOXIN, 1,2,3,4,7,8-HEXACHLORO-

Systematic Name

English

1,2,3,4,7,8-HEXACHLORODIBENZODIOXIN

Systematic Name

English

1,2,3,4,7,8-HEXACHLORODIBENZO(B,E)(1,4)DIOXIN [MI]

Common Name

English

PCDD 66

Common Name

English

Code System Code Type Description

MESH

C078219