U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 13:39:11 GMT 2023
Edited
by admin
on Sat Dec 16 13:39:11 GMT 2023
Nucleic Acid Type OLIGONUCLEOTIDE
Nucleic Acid Subtype
Record UNII
5QY760I44W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ISIS-333611
Common Name English
ISIS 333611
Code English
Code System Code Type Description
EPA CompTox
DTXSID50239560
Created by admin on Sat Dec 16 13:39:12 GMT 2023 , Edited by admin on Sat Dec 16 13:39:12 GMT 2023
PRIMARY
FDA UNII
5QY760I44W
Created by admin on Sat Dec 16 13:39:12 GMT 2023 , Edited by admin on Sat Dec 16 13:39:12 GMT 2023
PRIMARY
PUBCHEM
71587877
Created by admin on Sat Dec 16 13:39:12 GMT 2023 , Edited by admin on Sat Dec 16 13:39:12 GMT 2023
PRIMARY
CAS
937407-37-9
Created by admin on Sat Dec 16 13:39:12 GMT 2023 , Edited by admin on Sat Dec 16 13:39:12 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_6-1_15 10 / 20
2'-O-Methoxyethyl ribose 1_1-1_5;1_16-1_20 10 / 20
Linkage Site Range Site Count
Sodium Phosporothioate 1_2-1_20 19 / 19

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
NUCLEOSIDE_SUBSTITUTION [1_4] SITE_SPECIFIC 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE 9Q36I4D9VB
NUCLEOSIDE_SUBSTITUTION [1_1] [1_2] [1_5] [1_7] [1_17] [1_19] SITE_SPECIFIC 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE AOQ54IZZ6J