MAGNESIUM GLUTAMATE HYDROBROMIDE

Possibly Marketed Outside US

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C5H7NO4.Mg.BrH
Molecular Weight	250.33
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of MAGNESIUM GLUTAMATE HYDROBROMIDE

Structure Search

SMILES

[Mg++].Br.N[C@@H](CCC([O-])=O)C([O-])=O

InChI

InChIKey=IMSNBENJLMCAJL-QTNFYWBSSA-L

InChI=1S/C5H9NO4.BrH.Mg/c6-3(5(9)10)1-2-4(7)8;;/h3H,1-2,6H2,(H,7,8)(H,9,10);1H;/q;;+2/p-2/t3-;;/m0../s1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C5H7NO4
Molecular Weight	145.1134
Charge	-2
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	Mg
Molecular Weight	24.305
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://noshly.com/additive/e625/flavour-enhancer/625/ | http://www.thegoodscentscompany.com/data/rw1609401.html | http://www.foodadditiveslist.com/page/55/ | http://www.fao.org/ag/agn/jecfa-additives/specs/Monograph1/Additive-259.pdfhttps://www.ncbi.nlm.nih.gov/pubmed/680616 | http://www.druginfosys.com/drug.aspx?drugcode=1321&type=1

Magnesium glutamate hydrobromide (Psychoverlan) is a known sedative and muscle relaxant. In a long-term study 19 young females were treated with Psychoverlan capsules or syrup for an average of 11.4 months. Intolerance phenomena and side-effects were not seen. It was even decided to increase the standard dose. None of the patients developed brominism or bromine intoxication. The general state of health of 13 of the 19 subjects was improved by the harmonizing effect of the drug on psychic and vegetative functions. Tiredness and somnolence were not observed.

CNS Activity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Psychotic disorder 26 Sources: https://www.ncbi.nlm.nih.gov/pubmed/680616 https://www.ncbi.nlm.nih.gov/pubmed/4849930	Primary		Approved 8583	PSYCHOVERLAN Approved Use Nervous system disorders
Unknown 2596

PubMed

Title	Date	PubMed
Synthesis and biological evaluation of (-)-6-O-desmethylcryptopleurine and analogs.	2015-01-15	25499434
No enhancing effects of calcium/magnesium salts of L-glutamate and L-ascorbate on tumor development in a rat medium-term multiorgan carcinogenesis bioassay.	1993-05	8492329
[Long-term treatment with psychoverlan in children and adolescents with behavior disorders].	1978-08-24	680616
[The management of nervous disturbances with psychoverlan].	1974-05	4849930

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Oral

In Vitro Use Guide

60 g (0.160 mol) magnesium-L-glutamate-tetrahydrate in a spherical flask were suhmerged in the rotary evaporator under a vacuum of 50 mbar in an oil bath that had been preheated to 190C. The separation of water and the formation of the magnesium-L-pyroglutamate began after 2 minutes and ended after 45 minutes, a solid being involved at each stage of the reaction.

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:10:07 GMT 2025` Edited by `admin` on `Mon Mar 31 22:10:07 GMT 2025`
Record UNII	5Q5ZYJ43UH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MAGNESIUM GLUTAMATE HYDROBROMIDE

Systematic Name

English

L-GLUTAMIC ACID, MAGNESIUM SALT (1:1), HYDROBROMIDE

Preferred Name

English

Magnesium glutamate hydrobromide [WHO-DD]

Common Name

English

Code System Code Type Description

EVMPD

SUB14426MIG