SODIUM P-PHENOLSULFONATE DIHYDRATE

First approved in 1996

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H5O4S.Na.2H2O
Molecular Weight	232.187
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SODIUM P-PHENOLSULFONATE DIHYDRATE

Structure Search

SMILES

O.O.[Na+].OC1=CC=C(C=C1)S([O-])(=O)=O

InChI

InChIKey=SXONATFNYJWFNK-UHFFFAOYSA-M

InChI=1S/C6H6O4S.Na.2H2O/c7-5-1-3-6(4-2-5)11(8,9)10;;;/h1-4,7H,(H,8,9,10);;2*1H2/q;+1;;/p-1

HIDE SMILES / InChI

Molecular Formula	C6H5O4S
Molecular Weight	173.167
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.98976928
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4639458http://www.viacheminc.com/product/phenolsulfonic-acid/http://www.kosmetik-transparent.at/explandict/ammonium-phenolsulfonate | https://www.google.com.au/patents/US2449081
Curator's Comment: http://www.ncbi.nlm.nih.gov/pubmed/3937456 and http://compoundinglab.com.au/dental-products.html

Ammonium phenolsulfonate is an ingredient of deodorant, possesses antimicrobial properties to help the inhibition of the growth of microorganism of the skin. In addition, some studies were shown, that that ammonium para-hydroxy phenyl arsonate when used with phenolsulfonates in a concentration of 0.0238% in the drinking water was effective in the prevention of hemorrhage in chicks.

Originator

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2596
Unknown 2596
Aphthous ulcers 10 Sources: http://www.ncbi.nlm.nih.gov/pubmed/12987098	Curative	Approved 8583	Negatol Approved Use Aphthous ulcers

PubMed

Title	Date	PubMed
Cell-transforming activity of fourteen chemical agents used in dental practice in Syrian hamster embryo cells.	2003-12	14737023
Assessment of genotoxicity of dental antiseptics: ability of phenol, guaiacol, p-phenolsulfonic acid, sodium hypochlorite, p-chlorophenol, m-cresol or formaldehyde to induce unscheduled DNA synthesis in cultured Syrian hamster embryo cells.	2000-07	10952079
Juvenilizing activity of compounds related to the juvenile hormone against pupae of the stable fly.	1972-12	4639458

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:16:47 GMT 2025` Edited by `admin` on `Mon Mar 31 21:16:47 GMT 2025`
Record UNII	5NH81N759Q
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BENZENESULFONIC ACID, 4-HYDROXY-, SODIUM SALT, HYDRATE (1:1:2)

Preferred Name

English

SODIUM P-PHENOLSULFONATE DIHYDRATE

Common Name

English

BENZENESULFONIC ACID, P-HYDROXY-, MONOSODIUM SALT, DIHYDRATE

Systematic Name

English

BENZENESULFONIC ACID, 4-HYDROXY-, MONOSODIUM SALT, DIHYDRATE

Systematic Name

English

4-HYDROXYBENZENESULFONIC ACID SODIUM SALT DIHYDRATE

Systematic Name

English

SULPHOCARBOLATE SODIUM

Common Name

English

PHENOLSULPHONATE SODIUM

Common Name

English

Code System Code Type Description

FDA UNII

5NH81N759Q