TECHNETIUM 8-HYDROXYQUINOLINE TC-99M

First approved in 1973

Details

Stereochemistry	ACHIRAL
Molecular Formula	2C9H6NO.Tc
Molecular Weight	387.2063
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TECHNETIUM 8-HYDROXYQUINOLINE TC-99M

Structure Search

SMILES

[99Tc++].[O-]C1=C2N=CC=CC2=CC=C1.[O-]C3=C4N=CC=CC4=CC=C3

InChI

InChIKey=IQEZQKMRKHHSQE-FCHARDOESA-L

InChI=1S/2C9H7NO.Tc/c2*11-8-5-1-3-7-4-2-6-10-9(7)8;/h2*1-6,11H;/q;;+2/p-2/i;;1+1

HIDE SMILES / InChI

Molecular Formula	Tc
Molecular Weight	98.9063
Charge	2
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C9H6NO
Molecular Weight	144.15
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.hindawi.com/journals/stni/2014/839369/
Curator's Comment: description was created based on several sources, including https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401

Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2578
bone problems 43 Sources: https://www.drugs.com/cons/osteolite.html	Diagnostic	Approved 8429	OSTEOLITE Approved Use Unknown Launch Date 2.50992001E11
osteogenesis 43 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018035s032lbl.pdf	Diagnostic	Approved 8429	DRAXIMAGE MDP-10 Approved Use MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date 2.80972788E11

PubMed

Title	Date	PubMed

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:24:44 UTC 2023` Edited by `admin` on `Fri Dec 15 15:24:44 UTC 2023`
Record UNII	5KI22C5WOC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECHNETIUM 8-HYDROXYQUINOLINE TC-99M

Common Name

English

8-QUINOLINOL, TECHNETIUM-99TC SALT

Common Name

English

Code System Code Type Description

CAS

67000-55-9

Created by admin on Fri Dec 15 15:24:44 UTC 2023 , Edited by admin on Fri Dec 15 15:24:44 UTC 2023

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FDA UNII

5KI22C5WOC

Created by admin on Fri Dec 15 15:24:44 UTC 2023 , Edited by admin on Fri Dec 15 15:24:44 UTC 2023

PRIMARY

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