INDIUM IN-111 PENTETATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H18N3O10.In.2H
Molecular Weight	501.2278
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H+].[H+].[111In+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=BLALCKLYSDDAOC-JWFOFJTQSA-K

InChI=1S/C14H23N3O10.In/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);/q;+3/p-3/i;1-4

HIDE SMILES / InChI

Molecular Formula	In
Molecular Weight	110.905110677
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H20N3O10
Molecular Weight	390.3227
Charge	-3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugbank.ca/drugs/DB09425 | https://www.drugs.com/mmx/indium-in-111-pentetate.html

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
hydrocephalus 9 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8583	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
syringomyelia 9 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8583	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
arachnoid cyst 9 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8583	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982

Sample Use Guides

In Vivo Use Guide

The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 μCi. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:26:49 GMT 2025` Edited by `admin` on `Mon Mar 31 21:26:49 GMT 2025`
Record UNII	5K3UP561AX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INDIUM (111IN) PENTETATE

Preferred Name

English

INDIUM IN-111 PENTETATE

Common Name

English

INDIUM IN 111 PENTETATE

Common Name

English

INDATE(2-)-111IN, (N,N-BIS(2-(BIS(CARBOXYMETHYL)AMINO)ETHYL)GLYCINATO(5-))-, DIHYDROGEN

Systematic Name

English

INDIUM (111IN) PENTETIC ACID

Common Name

English

INDIUM DTPA IN 111

Common Name

English

Classification Tree Code System Code

WHO-VATC

QV09AX01