DescriptionCurator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/13912270
Curator's Comment: Description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/pubmed/13912270
Isoniazid pyruvate is a metabolite of isoniazid. Isoniazid (Laniazid, Nydrazid), also known as isonicotinylhydrazine (INH), is an organic compound that is the first-line medication in prevention and treatment of tuberculosis. It has been claimed that isoniazone pyruvate causes less excretion of pyridoxine than isoniazid and might therefore be less likely to cause peripheral neuritis.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Isocitrate lyase: a potential target for anti-tubercular drugs. | 2013-05 |
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| Synthesis and characterization of pyruvate-isoniazid analogs and their copper complexes as potential ICL inhibitors. | 2012-05-01 |
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| [STUDIES ON THE PHYSICOCHEMICAL PROPERTIES OF CALCIUM PYRUVATE ISONIAZONE. VIII. ON THE DISTRIBUTION EQUILIBRIUM OF ISONIAZIDE DERIVATIVES]. | 1963-08 |
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| A comparative study of the metabolism and toxicity of isoniazid and isoniazone calcium pyruvate. | 1962-03 |
Patents
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