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Details

Stereochemistry ACHIRAL
Molecular Formula Cr2O7.2H4N
Molecular Weight 252.0649
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMMONIUM DICHROMATE

SMILES

[NH4+].[NH4+].[O-][Cr](=O)(=O)O[Cr]([O-])(=O)=O

InChI

InChIKey=JOSWYUNQBRPBDN-UHFFFAOYSA-P
InChI=1S/2Cr.2H3N.7O/h;;2*1H3;;;;;;;/q;;;;;;;;;2*-1/p+2

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula Cr2H2O7
Molecular Weight 218.0039
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Sodium dichromate is an inorganic compound, containing hexavalent chromium. It is highly corrosive and is a strong oxidizing agent. Sodium dichromate is mainly used to produce other chromium compounds but is also used in drilling muds, in metal treatments, in wood preservatives, in the production of dyes and organic chemicals and as a corrosion inhibitor. Sodium dichromate primarily affects the respiratory system causing ulcerations, shortness of breath, bronchitis, pneumonia, and asthma but can also affect the gastrointestinal tract, liver, kidneys and immune system. This substance is a known human carcinogen and is associated with an increased risk of developing lung cancer and cancer of the sinonasal cavity.

Approval Year

PubMed

PubMed

TitleDatePubMed
Effects of Cr(VI) on the expression of the oxidative stress genes in human lung cells.
1998 Aug
Thiol-reactive metal compounds inhibit NF-kappa B activation by blocking I kappa B kinase.
2000 Jun 1
The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation.
2000 Sep
Comparison of the preventive effect of vitamin C and E on hexavalent chromium induced pulmonary fibrosis in rat.
2008 Aug
Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis.
2008 Aug
Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen species-mediated p53 activation in JB6 Cl41 cells.
2010 Jun 1
Nitric oxide-mediated bcl-2 stabilization potentiates malignant transformation of human lung epithelial cells.
2010 May
The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells.
2011 Feb
Hexavalent chromium inhibited the expression of RKIP of heart in vivo and in vitro.
2011 Feb
Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water.
2012 Feb 15
Long-term exposure to hexavalent chromium inhibits expression of tumor suppressor genes in cultured cells and in mice.
2012 Jun
Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish.
2014 Mar 10
Temporal changes in rat liver gene expression after acute cadmium and chromium exposure.
2015
Human bronchial epithelial BEAS-2B cells, an appropriate in vitro model to study heavy metals induced carcinogenesis.
2015 Sep 15
Hepatoprotective effect of Taraxacum officinale leaf extract on sodium dichromate-induced liver injury in rats.
2016 Mar
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 01:36:25 UTC 2023
Edited
by admin
on Sat Dec 16 01:36:25 UTC 2023
Record UNII
5J18BP595G
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AMMONIUM DICHROMATE
Systematic Name English
CHROMIC ACID (H2CR2O7), AMMONIUM SALT (1:2)
Common Name English
AMMONIUM DICHROMATE(VI) [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 68305
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
Code System Code Type Description
ECHA (EC/EINECS)
232-143-1
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
EPA CompTox
DTXSID70872953
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
FDA UNII
5J18BP595G
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
PUBCHEM
24600
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
MESH
C013811
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
CAS
7789-09-5
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
WIKIPEDIA
AMMONIUM DICHROMATE
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
HSDB
481
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY
MERCK INDEX
m1782
Created by admin on Sat Dec 16 01:36:25 UTC 2023 , Edited by admin on Sat Dec 16 01:36:25 UTC 2023
PRIMARY Merck Index