CAMPESTANOL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H50O
Molecular Weight	402.696
Optical Activity	UNSPECIFIED
Defined Stereocenters	10 / 10
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CC[C@@H](C)C(C)C

InChI

InChIKey=ARYTXMNEANMLMU-ATEDBJNTSA-N

InChI=1S/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C28H50O
Molecular Weight	402.696
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	10 / 10
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
[Plants sterols and stanols: new prospects in prevention of ischemic heart disease (based on data published in the European Heart Journal, 1999, vol. 1 (Suppl S))].	2001	11234137
Dietary vegetable oil and wood derived plant stanol esters reduce atherosclerotic lesion size and severity in apoE*3-Leiden transgenic mice.	2001 Aug	11472737
Effects of plant sterols and stanols on lipid metabolism and cardiovascular risk.	2001 Feb	11383323
Assessing plasma pharmacokinetics of cholesterol following oral coadministration with a novel vegetable stanol mixture to fasting rats.	2001 Jan	11064375
Accumulation of 6-deoxocathasterone and 6-deoxocastasterone in Arabidopsis, pea and tomato is suggestive of common rate-limiting steps in brassinosteroid biosynthesis.	2001 May	11382232
Short-term LDL cholesterol-lowering efficacy of plant stanol esters.	2002 Aug 27	12197945
Biosynthesis of cholestanol in higher plants.	2002 Jun	12031446
Consumption of tall oil-derived phytosterols in a chocolate matrix significantly decreases plasma total and low-density lipoprotein-cholesterol levels.	2002 Nov	12425728
Decrease in plasma low-density lipoprotein cholesterol, apolipoprotein B, cholesteryl ester transfer protein, and oxidized low-density lipoprotein by plant stanol ester-containing spread: a randomized, placebo-controlled trial.	2003 Apr	12679174
Comparison of the intestinal uptake of cholesterol, plant sterols, and stanols in mice.	2003 Mar	12562824
Analysis of plant sterol and stanol esters in cholesterol-lowering spreads and beverages using high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectroscopy.	2003 Sep 10	12952413
Comparison of cholesterol-lowering efficacy and anti-atherogenic properties of hydrogenated versus non-hydrogenated (Phytrol) tall oil-derived phytosterols in apo E-deficient mice.	2003 Sep-Nov	15107599
The missense mutation in Abcg5 gene in spontaneously hypertensive rats (SHR) segregates with phytosterolemia but not hypertension.	2005 Jul 18	16026620
Brassinosteroids are inherently biosynthesized in the primary roots of maize, Zea mays L.	2005 May	15896368
[Analysis of phytosterol contents in Chinese plant food and primary estimation of its intake of people].	2007 May	17712945
Efficacy and safety of disodium ascorbyl phytostanol phosphates in men with moderate dyslipidemia.	2008 Jul	18320185
Effects of long-term plant sterol or stanol ester consumption on lipid and lipoprotein metabolism in subjects on statin treatment.	2008 Nov	18846701
Co-administration of berberine and plant stanols synergistically reduces plasma cholesterol in rats.	2008 Nov	18430428
Dietary phytosterols and phytostanols alter the expression of sterol-regulatory genes in SHRSP and WKY inbred rats.	2009	19851062
Controversial role of plant sterol esters in the management of hypercholesterolaemia.	2009 Feb	19158117
Disodium ascorbyl phytostanol phosphate (FM-VP4), a modified phytostanol, is a highly active hypocholesterolaemic agent that affects the enterohepatic circulation of both cholesterol and bile acids in mice.	2010 Jan	19822032

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:47:01 GMT 2023` Edited by `admin` on `Fri Dec 15 15:47:01 GMT 2023`
Record UNII	5J08LF99N1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CAMPESTANOL

Systematic Name

English

DIHYDROCAMPESTERIN

Common Name

English

5.ALPHA.-ERGOSTAN-3.BETA.-OL, (24R)-

Systematic Name

English

NEOSPONGOSTEROL, DIHYDRO-

Common Name

English

24.BETA.-METHYLCHOLESTANOL

Common Name

English

ERGOSTAN-3-OL, (3.BETA.,5.ALPHA.,24R)-

Systematic Name

English

CHALINASTANOL

Common Name

English

5.ALPHA.-DIHYDROCAMPESTEROL

Common Name

English

Classification Tree Code System Code

DSLD

2402 (Number of products:2)