MOXAPRINDINE

Details

Stereochemistry	MIXED
Molecular Formula	C23H32N2O
Molecular Weight	352.513
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN(CC)CCCN(C1CC2=C(C=CC=C2)C1OC)C3=CC=CC=C3

InChI

InChIKey=QQGGXAOUSKREAE-UHFFFAOYSA-N

InChI=1S/C23H32N2O/c1-4-24(5-2)16-11-17-25(20-13-7-6-8-14-20)22-18-19-12-9-10-15-21(19)23(22)26-3/h6-10,12-15,22-23H,4-5,11,16-18H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C23H32N2O
Molecular Weight	352.513
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7178839 | https://www.ncbi.nlm.nih.gov/pubmed/7075647 | https://www.ncbi.nlm.nih.gov/pubmed/7215413 | https://www.ncbi.nlm.nih.gov/pubmed/7251236

Moxaprindine is a antiarrhythmic drug for the treatment of ventricular arrhythmias patented by Manufacture de Produits Pharmaceutiques A. Christiaens, S. A. In clinical studies Moxaprindine shows high efficacy in suppressing ventricular arrhythmias occurring before, during and after maximal exercise stress testing. This effect was obtained both in subjects with clinically normal hearts and in a limited number of patients with ischemic heart disease.

Originator

Approval Year

PubMed

Title	Date	PubMed
Effect of 2 anti-arrhythmic drugs aprindine and moxaprindine on the replication capacity of murine and human haemopoietic cells.	1982 Oct	7178839

Patents

Sample Use Guides

In Vivo Use Guide

2.5 mg/kg

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:14:50 UTC 2023` Edited by `admin` on `Fri Dec 15 18:14:50 UTC 2023`
Record UNII	5HAF6QO904
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MOXAPRINDINE

Official Name

English

moxaprindine [INN]

Common Name

English

N,N-DIETHYL-N'-(1-METHOXY-2-INDANYL)-N'-PHENYL-1,3-PROPANEDIAMINE

Systematic Name

English

Code System Code Type Description

ChEMBL

CHEMBL2104713