U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula Lu
Molecular Weight 174.967
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LUTETIUM

SMILES

[Lu]

InChI

InChIKey=OHSVLFRHMCKCQY-UHFFFAOYSA-N
InChI=1S/Lu

HIDE SMILES / InChI

Molecular Formula Lu
Molecular Weight 174.967
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Lutetium is a silvery-white, hard, dense metal. Lutetium is little used outside research. One of its few commercial uses is as a catalyst for cracking hydrocarbons in oil refineries. Lutetium-177 radionuclide is used in radiopharmaceutical therapy. FDA approved Lutetium-177 dotatate for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

Originator

Curator's Comment: The honour of discovering lutetium went to Georges Urbain at the Sorbonne in Paris, because he was the first to report it. The story began with the discovery of yttrium in 1794 from which several other elements – the rare earths (aka lanthanoids) – were to be separated, starting with erbium in 1843 and ending with lutetium in 1907. Other chemists, namely Karl Auer in Germany and Charles James in the USA, were about to make the same discovery. Indeed James, who was at the University of New Hampshire, was ahead of Urbain and had extracted quite a lot of the new metal, but he delayed publishing his research. A sample of pure lutetium metal itself was not made until 1953.

Approval Year

PubMed

PubMed

TitleDatePubMed
Evolving Important Role of Lutetium-177 for Therapeutic Nuclear Medicine.
2015
Lutetium-177 therapeutic radiopharmaceuticals: linking chemistry, radiochemistry, and practical applications.
2015 Apr 22
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:40:53 UTC 2023
Edited
by admin
on Fri Dec 15 18:40:53 UTC 2023
Record UNII
5H0DOZ21UJ
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LUTETIUM
MI  
Systematic Name English
CASSIOPEUM
Common Name English
LUTETIUM [MI]
Common Name English
LU
Common Name English
LUTETIUM, ELEMENTAL
Common Name English
LUTECIUM
Common Name English
Classification Tree Code System Code
DSLD 1241 (Number of products:27)
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
Code System Code Type Description
EVMPD
SUB177509
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
MERCK INDEX
m6946
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY Merck Index
RXCUI
1534772
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY RxNorm
CHEBI
33382
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
ECHA (EC/EINECS)
231-103-0
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
EPA CompTox
DTXSID5047746
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
FDA UNII
5H0DOZ21UJ
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
CAS
7439-94-3
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
DAILYMED
5H0DOZ21UJ
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
SMS_ID
100000163286
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
PUBCHEM
23929
Created by admin on Fri Dec 15 18:40:53 UTC 2023 , Edited by admin on Fri Dec 15 18:40:53 UTC 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY