Chloroacetic Acid

Details

Stereochemistry	ACHIRAL
Molecular Formula	C2H3ClO2
Molecular Weight	94.497
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)CCl

InChI

InChIKey=FOCAUTSVDIKZOP-UHFFFAOYSA-N

InChI=1S/C2H3ClO2/c3-1-2(4)5/h1H2,(H,4,5)

HIDE SMILES / InChI

Molecular Formula	C2H3ClO2
Molecular Weight	94.497
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Porcine small intestine submucosa (SIS) is not an acellular collagenous matrix and contains porcine DNA: possible implications in human implantation.	2005-04	15736287
Morphology, cytochemical staining, and ultrastructural characteristics of the blood cells of the giant lizard of El Hierro (Gallotia simonyi).	2005-04	15563919
Direct electrochemistry and electrocatalysis of hemoglobin in poly-3-hydroxybutyrate membrane.	2005-03-15	15681201
Primary myeloid sarcoma of the testicle with t(15;17).	2005-03	15721636
Myeloid sarcoma occurring in the maxillary gingiva: a case without leukemic manifestations.	2005-02	15765782
Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase.	2005-02	15720133
In vivo characterization of developing chronic pancreatitis in rats.	2005-02	15543202
Teaching cases from the Royal Marsden and St Mary's Hospital case 29: striking generalized lymphadenopathy in 'acute myeloid leukemia'.	2005-01	15621796
Kinetics of haloacetic acid reactions with Fe(0).	2004-12-15	15669353
Synthesis and structural characterization of bioactive peptide conjugates using thioether linkage approaches.	2004-12	15635622
A family of Mn16 single-molecule magnets from a reductive aggregation route.	2004-11-15	15530081
Synthesis and properties of N-hexadecyl ethylenediamine triacetic acid.	2004-11-15	15464823
Synthesis and evaluation of some novel quinazolinone derivatives as diuretic agents.	2004-10	15476284
Batch-test study on the dechlorination of 1,1,1-trichloroethane in contaminated aquifer material by zero-valent iron.	2004-10	15358490
Chemical and biological characterization of newly discovered iodoacid drinking water disinfection byproducts.	2004-09-15	15487777
Genetic organization of the dhlA gene encoding 1,2-dichloroethane dechlorinase from Xanthobacter flavus UE15.	2004-09	15459646
One pot synthesis of thiazolodihydropyrimidinones and evaluation of their anticancer activity.	2004-09	15337290
Direct detection of trace haloacetates in drinking water using microbore ion chromatography. Improved detector sensitivity using a hydroxide gradient and a monolithic ion-exchange type suppressor.	2004-08-27	15460250
Stereoselective chloroacetate aldol reactions: syntheses of acetate aldol equivalents and darzens glycidic esters.	2004-08-05	15281754
Haloacetic acids in the aquatic environment. Part II: ecological risk assessment.	2004-08	15182971
Haloacetic acids in the aquatic environment. Part I: macrophyte toxicity.	2004-08	15182970
Granulocyte colony-stimulating factor synergistically augments 1,25-dihydroxyvitamin D3-induced monocytic differentiation in murine bone marrow cell cultures.	2004-07	15305226
Effects of superoxide dismutase and polyclonal tumor necrosis factor-alpha antibodies on chloroacetate-induced cellular death and superoxide anion production by J774.A1 macrophages.	2004-06	15450858
Identification of the major vanilloid component in Capsicum extract by HPLC-EC and HPLC-MS.	2004-05-01	15116943
Biodegradation of haloacetic acids by bacterial enrichment cultures.	2004-05	15041296
Diastereoselective synthesis of cularine alkaloids via enium ions and an easy entry to isoquinolines by aza-Wittig electrocyclic ring closure.	2004-04-30	15104427
Change of monochloroacetic acid to biodegradable organic acids by hydrothermal reaction.	2004-04-30	15081173
The weakly coordinating trichloromethanesulfonate anion: NQR comparison of its coordinating abilities via oxygen with those of the chloroacetate ions.	2004-03-22	15018526
[Study on a new antarthritic injection--O-carboxymethyl chitosan].	2004-02	15022456
Phase I clinical trial of the bispecific antibody MDX-H210 (anti-FcgammaRI x anti-HER-2/neu) in combination with Filgrastim (G-CSF) for treatment of advanced breast cancer.	2003-12-15	14676800
Evaluation of the influence of chloroacetic acids on the pharmacokinetics of trihalomethanes in the rat.	2003-12-12	14612337
Novel 3,3a,4,5,6,7-hexahydroindazole and arylthiazolylpyrazoline derivatives as anti-inflammatory agents.	2003-12	14677148
Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents.	2003-11-15	14599561
An unusual cause of burn injury: skin exposure to monochloroacetic acid.	2003-11-12	14610430
Synthesis of some new thiazole derivatives of pharmaceutical interest.	2003-11	14971309
Kinetics of monochloroacetic acid at subtoxic and toxic doses in rats after single oral and dermal administrations.	2003-11	12915718
Systemic effects and skin injury after experimental dermal exposure to monochloroacetic acid.	2003-10	15747777
Extramedullary acute myeloid leukemia (granulocytic sarcoma) with arm paresis, maculopapular exanthema and organ involvement.	2003-09	14565668
Synthesis of some new benzothiazole derivatives as potential antimicrobial and antiparasitic agents.	2003-08	12967026
NaF induces early differentiation of murine bone marrow cells along the granulocytic pathway but not the monocytic or preosteoclastic pathway in vitro.	2003-07-24	12880368
Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis.	2003-07-23	12862480
Airborne haloacetic acids.	2003-07-01	12875391
Detection of inflammation following renal ischemia by magnetic resonance imaging.	2003-07	12787394
Determination of chloroacetates in atmospheric particulate matter.	2003-06-01	12831014
Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model.	2003-06	12875872
Vacancy ion-exclusion chromatography of haloacetic acids on a weakly acidic cation-exchange resin.	2003-05-16	12830885
The in vitro differentiation of mouse embryonic stem cells into neutrophils.	2003	14696342
[Occupational risk and evaluation of health damage in workers engaged in organochlorine compound production].	2003	14593650
Therapeutic effects of glucose infusion on monochloroacetic acid exposure in rats.	2002-09	15119527
Myelogenous leukemia in a bearded dragon (Acanthodraco vitticeps).	2001-03	12790401

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:16:37 GMT 2025` Edited by `admin` on `Mon Mar 31 19:16:37 GMT 2025`
Record UNII	5GD84Y125G
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MONOCHLOROACETIC ACID

Preferred Name

English

Chloroacetic Acid

Official Name

English

ACETIC ACID, CHLORO-

Common Name

English

2-CHLOROACETIC ACID

Systematic Name

English

Monochloroacetic acid [WHO-DD]

Common Name

English

CHLOROACETIC ACID [ISO]

Common Name

English

MONOCHLOROACETIC ACID [VANDF]

Common Name

English

CHLOROETHANOIC ACID

Systematic Name

English

CHLOROACETIC ACID [MI]

Common Name

English

MONOCHLOROACETIC ACID [MART.]

Common Name

English

NSC-142

Code

English

CHLOROACETIC ACID [HSDB]

Common Name

English

CHLOROACETIC ACID [VANDF]

Common Name

English

CHLOROACETATE

Systematic Name

English

Classification Tree Code System Code

CFR

21 CFR 189.155