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IDURSULFASE BETA
5GCF8EPY6R
Possibly Marketed Outside US
General
Record Details
Names
7
Classification
2
Identifiers
5
Subunits
1
Disulfide Links
2
Glycosylation
8
Active Moiety
1
Modifications
1
Characteristic Attributes
2
IDURSULFASE BETA
5GCF8EPY6R
Possibly Marketed Outside US
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
5GCF8EPY6R
Record Status
Validated (UNII)
Record Version
10
9
8
7
6
5
4
3
2
1
Names
7
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5
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entries
Name
Type
Language
Name
Type
Language
IDURSULFASE BETA
Official Name
English
HUNTERASE
Preferred Name
English
Idursulfase beta [WHO-DD]
Common Name
English
idursulfase beta [INN]
Common Name
English
IDURONATE 2-SULFATASE (A-L-IDURONATE SULFATE SULFATASE), HUMAN PROENZYME PRODUCED IN CHO CELLS (GLYCOFORM BETA)
Common Name
English
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Classification
2
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Classification Tree
Code System
Code
Classification Tree
Code System
Code
Enzymes
ATC
ALIMENTARY TRACT AND METABOLISM
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Enzymes
idursulfase beta
WHO-ATC
A16AB16
Designated
ORPHAN DRUG
Designated
Treatment of Hunter Syndrome (mucopolysaccharidoses)
FDA ORPHAN DRUG
385712
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Identifiers
5
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
FDA UNII
5GCF8EPY6R
PRIMARY
SMS_ID
100000178235
PRIMARY
INN
9504
PRIMARY
CAS
1271734-34-9
PRIMARY
NCI_THESAURUS
C166846
PRIMARY
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Subunits
1
Subunit 0
>SUBUNIT_0
Disulfide Links
2
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From
To
From
To
1_146
1_159
1_397
1_407
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Glycosylation
8
Glycosylation Type
HUMAN
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Glycosylation Link Type
Site
Glycosylation Link Type
Site
N
1_6
N
1_90
N
1_119
N
1_221
N
1_225
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Active Moiety
1
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entries
Related Record
Type
Details
Related Record
Type
Details
5GCF8EPY6R
IDURSULFASE BETA
ACTIVE MOIETY
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Modifications
1
Structural Modifications
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Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO_ACID_SUBSTITUTION
[1_59]
Ala
3-OXO-ALANINE
3LXS1M9IE5
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C2689H4035N699O794S13
MOL_WEIGHT:NUMBER(CALCULATED)
CHEMICAL
ESTIMATED 59300 Da (average)
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