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Details

Stereochemistry ACHIRAL
Molecular Formula 2C2H5NO3.ClH
Molecular Weight 218.593
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AMINOOXYACETIC ACID HEMIHYDROCHLORIDE

SMILES

Cl.NOCC(O)=O.NOCC(O)=O

InChI

InChIKey=KBXIJIPYZKPDRU-UHFFFAOYSA-N
InChI=1S/2C2H5NO3.ClH/c2*3-6-1-2(4)5;/h2*1,3H2,(H,4,5);1H

HIDE SMILES / InChI

Molecular Formula C2H5NO3
Molecular Weight 91.066
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Kynurenic acid leads, dopamine follows: a new case of volume transmission in the brain?
2007-01
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells.
2006-07-25
Hydrogen sulfide inhibits nitric oxide production and nuclear factor-kappaB via heme oxygenase-1 expression in RAW264.7 macrophages stimulated with lipopolysaccharide.
2006-07-01
Nonezymatic formation of succinate in mitochondria under oxidative stress.
2006-07-01
Oligosaccharide microarrays fabricated on aminooxyacetyl functionalized glass surface for characterization of carbohydrate-protein interaction.
2006-02-15
Neuronal and astrocytic shuttle mechanisms for cytosolic-mitochondrial transfer of reducing equivalents: current evidence and pharmacological tools.
2006-02-14
High plasma cyst(e)ine level may indicate poor clinical outcome in patients with acute stroke: possible involvement of hydrogen sulfide.
2006-02
Enzymatic and mechanistic studies on the formation of N-phenylglycolohydroxamic acid from nitrosobenzene and pyruvate in spinach leaf homogenate.
2006-01-25
Transamination in the metabolism of the nephrotoxicant N-(3,5-dichlorophenyl)succinimide in rats.
2005-12
Effect of aminooxyacetic acid on extracellular level of D-serine in rat striatum: an in vivo microdialysis study.
2005-11-21
Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools.
2005-10-19
Cultures of rat astrocytes challenged with a steady supply of glutamate: new model to study flux distribution in the glutamate-glutamine cycle.
2005-09
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in oligodendrocyte cell line (OLN-93).
2005-08
Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice.
2005-08
Gamma-aminobutyric acid and mefloquine-induced seizures in mice.
2005-07
Demonstration of kynurenine aminotransferases I and II and characterization of kynurenic acid synthesis in cultured cerebral cortical neurons.
2005-06-01
Differential expression of genes encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis during hypoxia.
2005-05
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia.
2005-04-20
Automorphosis of etiolated pea seedlings in space is simulated by a three-dimensional clinostat and the application of inhibitors of auxin polar transport.
2005-04
Enhancement of photorespiration in immobilized Chlamydomonas reinhardtii cells.
2005-02
Chronic exposure to beta-hydroxybutyrate inhibits glucose-induced insulin release from pancreatic islets by decreasing NADH contents.
2005-02
Isolation and characterization of cytosolic alanine aminotransferase isoforms from starved rat liver.
2004-12
Nitrogen-15 NMR studies of nitrogen metabolism in Picea glauca buds.
2004-12
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis.
2004-10-07
Aminooxyacetic acid inhibits antheridiogenesis and development of Anemia phyllitidis gametophytes.
2004-10
Opioid modulation of GABA release in the rat inferior colliculus.
2004-09-07
Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase.
2004-08-31
Inhibition of [(15)N]valine transamination during selective labeling of barstar in a T7 polymerase system.
2004-07
Androgen secretion by Rcho-1 cells is independent of extracellular glutamate concentration.
2004-07
Differential in vitro development of inflorescences in long and short day Lemna spp.: involvement of ethylene and polyamines.
2004-06
Energy substrate requirements of rat retinal pigmented epithelial cells in culture: relative importance of glucose, amino acids, and monocarboxylates.
2004-04
Cellular glutathione prevents cytolethality of monomethylarsonic acid.
2004-03-01
Kynurenic acid production in cultured bovine aortic endothelial cells. Homocysteine is a potent inhibitor.
2004-03
A proteomic analysis identifies glutathione S-transferase isoforms whose abundance is differentially regulated by ethylene during the formation of early root epidermis in Arabidopsis seedlings.
2004-02-20
Reactive oxygen and ethylene are involved in the regulation of regurgitant-induced responses in bean plants.
2004-02
Purification and properties of cytosolic alanine aminotransferase from the liver of two freshwater fish, Clarias batrachus and Labeo rohita.
2004-02
Retinal function loss after monocarboxylate transport inhibition.
2004-02
Enhanced survival effect of pyruvate correlates MAPK and NF-kappaB activation in hydrogen peroxide-treated human endothelial cells.
2004-02
Distinct trans-plasma membrane redox pathways reduce cell-impermeable dyes in HeLa cells.
2004
Does ethylene mediate cluster root formation under iron deficiency?
2003-11
13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line.
2003-11
Modulation of endogenous production of H2S in rat tissues.
2003-09
Mechanisms of pyruvate inhibition of oxidant-induced apoptosis in human endothelial cells.
2003-09
Overproduced ethylene causes programmed cell death leading to temperature-sensitive lethality in hybrid seedlings from the cross Nicotiana suaveolens x N. tabacum.
2003-09
Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
2003-07
The metabolic pathway of salicylic acid rather than of chlorogenic acid is involved in the stress-induced flowering of Pharbitis nil.
2003-05
Ethylene insensitivity modulates ozone-induced cell death in birch.
2003-05
Effects of some GABAergic agents on quinine-induced seizures in mice.
1992-07-15
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
1992-06-19
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
1992-03
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:15:07 GMT 2025
Edited
by admin
on Mon Mar 31 22:15:07 GMT 2025
Record UNII
5G5QI2GN7A
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-40358
Preferred Name English
AMINOOXYACETIC ACID HEMIHYDROCHLORIDE
Common Name English
NSC-50782
Code English
NSC-56446
Code English
Code System Code Type Description
EPA CompTox
DTXSID50883906
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
ECHA (EC/EINECS)
220-862-3
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
NSC
50782
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
FDA UNII
5G5QI2GN7A
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
NSC
56446
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
CAS
2921-14-4
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
CHEBI
156302
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
NSC
40358
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
PUBCHEM
2723609
Created by admin on Mon Mar 31 22:15:07 GMT 2025 , Edited by admin on Mon Mar 31 22:15:07 GMT 2025
PRIMARY
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ACTIVE MOIETY