U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C10H8O8S2.2H2O
Molecular Weight 356.326
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHROMOTROPIC ACID DIHYDRATE

SMILES

O.O.OC1=CC(=CC2=CC(=CC(O)=C12)S(O)(=O)=O)S(O)(=O)=O

InChI

InChIKey=XGKPOHNAAOITPE-UHFFFAOYSA-N
InChI=1S/C10H8O8S2.2H2O/c11-8-3-6(19(13,14)15)1-5-2-7(20(16,17)18)4-9(12)10(5)8;;/h1-4,11-12H,(H,13,14,15)(H,16,17,18);2*1H2

HIDE SMILES / InChI

Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H8O8S2
Molecular Weight 320.296
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Aromatic sulfonic acids as viral inhibitors. Structure-activity study using rhino, adeno 3, herpes simplex, and influenza viruses.
1971 Jul
Inhibition of HIV replication by derivatives of naphthalenedisulfonic acids.
1990 Aug
Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities.
1992 Dec 25
Continuous flow system for the determination of trace boron in iron and steel utilizing in-line preconcentration/separation by Sephadex column coupled with fluorimetric detection.
2001 Aug 30
Resonance Rayleigh-scattering method for the determination of proteins with some monoazo dyes of chromotropic acid.
2001 Feb
Anion exchanger as a reaction/separation medium-absorptiometric determination of trace amounts of boron in waters by on-line complexation with chromotropic acid presorbed on the anion-exchange column.
2002 Dec
Preconcentration of lead with Amberlite XAD-2 and Amberlite XAD-7 based chelating resins for its determination by flame atomic absorption spectrometry.
2002 Mar 11
Presence of formaldehyde in topical corticosteroid preparations available on the Swedish market.
2003 Apr
Ion-association method for the colorimetric determination of neomycin sulphate in pure and dosage forms.
2003 Mar 1
Investigation of the reaction of magnesium with p-nitro-o-carboxylazochromotropic acid and the determination of magnesium in plants and in water.
2003 Mar-Apr
Chromotropic acid-formaldehyde reaction in strongly acidic media. The role of dissolved oxygen and replacement of concentrated sulphuric acid.
2003 May 28
Chemiluminometric measurement of atmospheric ozone with photoactivated chromotropic acid.
2003 Nov 1
Designer ligands for beryllium.
2004 Aug 11
Chromotropic acid, a fluorogenic chelating agent for aluminium(III).
2004 Jan
Detection of formaldehyde in textiles by chromotropic acid method.
2004 Nov-Dec
Spectroscopic studies on some azo compounds and their cobalt, copper and nickel complexes.
2004 Oct
Development of a solid surface fluorescence-based sensing system for aluminium monitoring in drinking water.
2005 Mar 15
A new enzymo-chemical method for simultaneous assay of methanol and formaldehyde.
2005 May-Jun
Factorial design for optimization of experimental variables in preconcentration of copper by a chromotropic acid loaded Q-Sepharose adsorbent.
2005 Nov 15
Disulphide reaction staining for the identification of integumental elastic fibres.
2005 Oct
Testing electrostatic complementarity in enzyme catalysis: hydrogen bonding in the ketosteroid isomerase oxyanion hole.
2006 Apr
Chromotropic acid-functionalized polyurethane foam: A new sorbent for on-line preconcentration and determination of cobalt and nickel in lettuce samples.
2006 Jun
Flow and sequential injection methods for the spectrofluorimetric determination of aluminium in pharmaceutical products using chromotropic acid as chromogenic reagent.
2006 Jun 16
Flow injection direct spectrophotometric assay for the speciation of trace chromium(III) and chromium(VI) using chromotropic acid as chromogenic reagent.
2006 May 15
Application of pneumatic flow injection-tandem spectrometer system for chromium speciation.
2007
Selective stopped-flow sequential injection method for the spectrophotometric determination of titanium in dental implant and natural Moroccan phosphate rock.
2007 Feb 28
Spectrophotometric determination of V(V) in environmental, biological, pharmaceutical and alloy samples by novel oxidative coupling reactions.
2007 Feb 9
Cloud point extraction of palladium in water samples and alloy mixtures using new synthesized reagent with flame atomic absorption spectrometry (FAAS).
2007 Jun 1
Stepwise complexometric determination of aluminium, titanium and iron concentrations in silica sand and allied materials.
2007 Oct 19
Complexes of chromium(III) with 2,3-dihydroxynaphthalene-6-sulfonic acid and 4,5-dihydroxynaphthalene-2,7-disulfonic acid in aqueous solution.
2008 Jun
[The expression of collagen I during mandibular fracture healing with the inferior alveolar nerve mutilated].
2008 Oct
Development and validation of spectrophotometric methods for estimating amisulpride in pharmaceutical preparations.
2010
Spectrophotometric determination of sildenafil citrate in pure form and in pharmaceutical formulation using some chromotropic acid azo dyes.
2010 Apr
Formaldehyde in the indoor environment.
2010 Apr 14
Novel naphthalene-based inhibitors of Trypanosoma brucei RNA editing ligase 1.
2010 Aug 24
Ultraviolet spectrophotometric method for determination of gelatin crosslinking in the presence of amino groups.
2010 Jan
Formaldehyde exposure and patterns of concomitant contact allergy to formaldehyde and formaldehyde-releasers.
2010 Jul
Fruit and soil quality of organic and conventional strawberry agroecosystems.
2010 Sep 1
Flow-injection determination of hydrogen peroxide based on fluorescence quenching of chromotropic acid catalyzed with Fe(II).
2010 Sep 15
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Dec 16 05:54:24 GMT 2023
Edited
by admin
on Sat Dec 16 05:54:24 GMT 2023
Record UNII
5FK3NDJ853
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHROMOTROPIC ACID DIHYDRATE
MI  
Common Name English
2,7-NAPHTHALENEDISULFONIC ACID, 4,5-DIHYDROXY-, HYDRATE (1:2)
Common Name English
CHROMOTROPIC ACID DIHYDRATE [MI]
Common Name English
2,7-NAPHTHALENEDISULFONIC ACID, 4,5-DIHYDROXY-, DIHYDRATE
Common Name English
Code System Code Type Description
FDA UNII
5FK3NDJ853
Created by admin on Sat Dec 16 05:54:24 GMT 2023 , Edited by admin on Sat Dec 16 05:54:24 GMT 2023
PRIMARY
CAS
5808-44-6
Created by admin on Sat Dec 16 05:54:24 GMT 2023 , Edited by admin on Sat Dec 16 05:54:24 GMT 2023
PRIMARY
EPA CompTox
DTXSID20206800
Created by admin on Sat Dec 16 05:54:24 GMT 2023 , Edited by admin on Sat Dec 16 05:54:24 GMT 2023
PRIMARY
PUBCHEM
71586819
Created by admin on Sat Dec 16 05:54:24 GMT 2023 , Edited by admin on Sat Dec 16 05:54:24 GMT 2023
PRIMARY
MERCK INDEX
m3515
Created by admin on Sat Dec 16 05:54:24 GMT 2023 , Edited by admin on Sat Dec 16 05:54:24 GMT 2023
PRIMARY Merck Index
Related Record Type Details
ANHYDROUS->SOLVATE