TIPETROPIUM BROMIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C25H32NOS.Br
Molecular Weight	474.497
Optical Activity	( + / - )
Defined Stereocenters	5 / 5
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[Br-].[H][C@]3(O[C@H]1C[C@@H]2CC[C@@H](C1)[N@+]2(C)CCC)C4=C(CSC5=C3C=CC=C5)C=CC=C4

InChI

InChIKey=FMUHIHWMPMORRQ-RXFBMFBMSA-M

InChI=1S/C25H32NOS.BrH/c1-3-14-26(2)19-12-13-20(26)16-21(15-19)27-25-22-9-5-4-8-18(22)17-28-24-11-7-6-10-23(24)25;/h4-11,19-21,25H,3,12-17H2,1-2H3;1H/q+1;/p-1/t19-,20-,21-,25-,26+;/m0./s1

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C25H32NOS
Molecular Weight	394.593
Charge	1
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6587997 | https://www.ncbi.nlm.nih.gov/pubmed/517068 | Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1208, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | https://apps.who.int/iris/bitstream/handle/10665/275695/WHO-EMP-RHT-TSN-2018.1-eng.pdf

Tipetropium is atropine derivative. It is the adrenoceptor agonist. Tipetropium is bronchospasmolytic agent. It was used as anti-asthmatic drug.

Approval Year

PubMed

Title	Date	PubMed
[Lung function studies with the bronchodilator terbutaline].	1979	517068
Comparison of the effects of a new anticholinergic drug (AA 28-263, Sandoz) and terbutaline in a dose-response study in endogenous asthmatics.	1984	6587997

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:04:56 GMT 2023` Edited by `admin` on `Fri Dec 15 16:04:56 GMT 2023`
Record UNII	5F8F2A90IA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIPETROPIUM BROMIDE

Official Name

English

tipetropium bromide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29704