ELGEMTUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:58:28 GMT 2025` Edited by `admin` on `Mon Mar 31 21:58:28 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	5F1CN52GFM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NOV-6

Preferred Name

English

ELGEMTUMAB

Official Name

English

LJM716

Code

English

Elgemtumab [WHO-DD]

Common Name

English

69745P00P9

Common Name

English

LJM-716

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN NEUREGULIN RECEPTOR HER3) (HUMAN MONOCLONAL CLONE NVS201010 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CLONE NVS201010 .KAPPA.-CHAIN, DIMER

Common Name

English

elgemtumab [INN]

Common Name

English

Code System Code Type Description

INN

10041

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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FDA UNII

5F1CN52GFM

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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NCI_THESAURUS

C101895

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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DRUG BANK

DB15430

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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SMS_ID

100000177050

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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LEGACY_FDA_UNII

69745P00P9

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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CAS

1512559-37-3

Created by admin on Mon Mar 31 21:58:28 GMT 2025 , Edited by admin on Mon Mar 31 21:58:28 GMT 2025

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From	To
1_22	1_96
1_144	1_200
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_261	2_321
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_220	3_214
2_220	4_214
1_226	2_226
1_229	2_229

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					RSO83C9PIA

RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3

TARGET -> INHIBITOR

Related Record Type Details


					5F1CN52GFM

ACTIVE MOIETY

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
amino acid substitution	[1_1] [2_1]	N-TERMINUS	Glu		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL