U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C4F6O3
Molecular Weight 210.0314
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Trifluoroacetic anhydride

SMILES

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

InChIKey=QAEDZJGFFMLHHQ-UHFFFAOYSA-N
InChI=1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

HIDE SMILES / InChI

Molecular Formula C4F6O3
Molecular Weight 210.0314
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Isolated hypoxic hepatic perfusion with retrograde outflow in patients with irresectable liver metastases; a new simplified technique in isolated hepatic perfusion.
2008-05
Enantioselective gas chromatographic analysis of aqueous samples by on-line derivatisation. Application to enzymatic reactions.
2008-02-29
Characterization and evaluation of the hydrolytic stability of trifluoroacetylated cellulose fibers.
2007-12-15
Regioselective and stereospecific acylation across oxirane- and silyloxy systems as a novel strategy to the synthesis of enantiomerically pure mono-, di- and triglycerides.
2007-12-07
Fast gas chromatography and negative-ion chemical ionization tandem mass spectrometry for forensic analysis of cannabinoids in whole blood.
2007-11-05
1-(N-trifluoroacetylamino)alkylphosphonic acids: synthesis and properties.
2007-11
Transition-metal/Lewis acid free synthesis of acyl benzothiophenes via C-C bond forming reaction.
2007-10-25
Analysis of abamectin residues in avocados by high-performance liquid chromatography with fluorescence detection.
2007-09-21
Conversion of nocathiacin I to nocathiacin acid by a mild and selective cleavage of dehydroalanine.
2007-09-14
Pipette tip solid-phase extraction and gas chromatography - mass spectrometry for the determination of methamphetamine and amphetamine in human whole blood.
2007-09
Simultaneous determination of methamphetamine and amphetamine in human urine using pipette tip solid-phase extraction and gas chromatography-mass spectrometry.
2007-06-28
MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.
2007-06-13
Gas chromatography-mass spectrometry characterization of the varnish and glue of an ancient 18th century double bass.
2007-04-20
A microwave-assisted synthesis of julolidine-9-carboxamide derivatives and their conversion to chalcogenoxanthones via directed metalation.
2007-03-30
[Gas chromatography with mass-selective detector in testing blood for amitriptyline and nortriptyline].
2007-03-07
The derivatisation of avermectins and milbemycins in milk: new insights and improvement of the procedure.
2007-02-28
Synthesis of perfluoroalkyl-substituted azines via nucleophilic substitution of hydrogen with perfluoroisopropyl carbanions.
2007-02-16
Rhenium(VII) oxide catalyzed heteroacylative ring-opening dimerization of tetrahydrofuran.
2007-02-07
Analytical procedure for determination of the time profile of eprinomectin excretion in sheep faeces.
2007-02
Facile N...N coupling of manganese(V) imido species.
2007-01-31
Albumin adducts of electrophilic benzene metabolites in benzene-exposed and control workers.
2007-01
Nucleophilic addition to N-phosphinylimines by rare-earth-metal triflate/trifluoroacetic anhydride activation.
2007
A single glucose derivative suitable for gas chromatography/mass spectrometry and gas chromatography/combustion/isotope ratio mass spectrometry.
2007
Determination of hydrolytic degradation products of nerve agents by injection port fluorination in gas chromatography/mass spectrometry for the verification of the Chemical Weapons Convention.
2007
Simultaneous determination of psychotropic phenylalkylamine derivatives in human hair by gas chromatography/mass spectrometry.
2007
Stereoselective synthesis of 2,4,6-trisubstituted tetrahydropyrans by the use of cyclopropanols as homoenols.
2007
A 'cold synthesis' of heroin and implications in heroin signature analysis utility of trifluoroacetic/acetic anhydride in the acetylation of morphine.
2006-12-20
A new synthesis of 2-sulfanyl allylic alcohols and alpha-sulfanyl ketones from carbonyl compounds and 1-chloroalkyl p-tolyl sulfoxides with carbon-carbon bond-formation.
2006-12
Oxidations of secondary alcohols to ketones using easily recyclable bis(trifluoroacetate) adducts of fluorous alkyl iodides, CF3(CF2)(n-1)I(OCOCF3)2.
2006-09-15
The study of metabolite-to-parent drug ratios of methamphetamine and methylenedioxymethamphetamine in hair.
2006-09-12
Reversible hydrophobization and lipophobization of cellulose fibers via trifluoroacetylation.
2006-09-01
Determination of carbofuran, carbaryl and their main metabolites in plasma samples of agricultural populations using gas chromatography-tandem mass spectrometry.
2006-08
Validation of the immunalysis microplate ELISA for the detection of methamphetamine in hair.
2006-07-29
Solid-phase column chromatographic and gas chromatographic-mass spectrometric determination of heptaminol in human urine and related pharmacokinetic profiles.
2006-07-29
Fluorinated acyclo-C-nucleoside analogues from glycals in two steps.
2006-07-24
[Determination of selenomethionine in selenium-enriched yeast by gas chromatography-mass spectrometry].
2006-05
Solid-phase extraction-gas chromatography and solid-phase extraction-gas chromatography-mass spectrometry determination of corrosion inhibiting long-chain primary alkyl amines in chemical treatment of boiler water in water-steam systems of power plants.
2006-04-28
Gas chromatographic-tandem mass spectrometric method for the quantitation of carbofuran, carbaryl and their main metabolites in applicators' urine.
2006-03-03
Liquid chromatographic assay of ivermectin in human plasma for application to clinical pharmacokinetic studies.
2006-03-03
Interference from a glucuronide metabolite in the determination of ramipril and ramiprilat in human plasma and urine by gas chromatography-mass spectrometry.
2006-02-24
Uncharged isocoumarin-based inhibitors of urokinase-type plasminogen activator.
2006-02-08
Synthesis and biological evaluation of some hydroxypyrazole derivatives as anti-inflammatory-antimicrobial agents.
2006-02
The first examples of Nazarov cyclizations leading to annulated pyrroles.
2006-01-05
Analysis of paraphenylenediamine.
2006
Simultaneous determination of amphetamines and ketamines in urine by gas chromatography/mass spectrometry.
2006
An improved method for the synthesis of nucleoside triphosphate analogues.
2005-12-09
Analysis of creatine, creatinine, creatine-d3 and creatinine-d3 in urine, plasma, and red blood cells by HPLC and GC-MS to follow the fate of ingested creatine-d3.
2005-12-05
Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers.
2005-11-14
Simple methods for the direct assembly, functionalization, and patterning of acid-terminated monolayers on Si111.
2005-11-08
Synthesis of TiO2 photocatalysts in supercritical CO2 via a non-hydrolytic route.
2005-10-13
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:56:44 GMT 2025
Edited
by admin
on Mon Mar 31 18:56:44 GMT 2025
Record UNII
5ENA87IZHT
Record Status Validated (UNII)
Record Version
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Name Type Language
NSC-96965
Preferred Name English
Trifluoroacetic anhydride
Systematic Name English
Hexafluoroacetic anhydride
Systematic Name English
TRIFLUOROACETIC ACID ANHYDRIDE
Systematic Name English
Bis(trifluoroacetic) anhydride
Systematic Name English
2,2,2-Trifluoroacetic anhydride
Systematic Name English
Code System Code Type Description
NSC
96965
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
EPA CompTox
DTXSID90861920
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
WIKIPEDIA
TRIFLUOROACETIC ANHYDRIDE
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
PUBCHEM
9845
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
CAS
407-25-0
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
FDA UNII
5ENA87IZHT
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY
ECHA (EC/EINECS)
206-982-9
Created by admin on Mon Mar 31 18:56:44 GMT 2025 , Edited by admin on Mon Mar 31 18:56:44 GMT 2025
PRIMARY