Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C47H51NO14 |
| Molecular Weight | 853.9061 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 11 / 11 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](OC(C)=O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C5=CC=CC=C5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@@H](O)[C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7
InChI
InChIKey=RCINICONZNJXQF-MEUUVHMJSA-N
InChI=1S/C47H51NO14/c1-25-31(60-43(56)36(52)35(28-16-10-7-11-17-28)48-41(54)29-18-12-8-13-19-29)23-47(57)40(61-42(55)30-20-14-9-15-21-30)38-45(6,32(51)22-33-46(38,24-58-33)62-27(3)50)39(53)37(59-26(2)49)34(25)44(47,4)5/h7-21,31-33,35-38,40,51-52,57H,22-24H2,1-6H3,(H,48,54)/t31-,32-,33+,35-,36-,37+,38-,40-,45+,46-,47+/m0/s1
| Molecular Formula | C47H51NO14 |
| Molecular Weight | 853.9061 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 10 / 11 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
NSC-LSC1 is a novel compound having an antitumor activity belonging to an analogue of taxol. As with the taxol, the NSC-LSC1 has a low toxicity and a high antitumor activity. NSC-LSC1 exhibits a high proliferation inhibitory activity against human or animal cancer cells transplanted into a test animal and further, a low toxicity to the animal which renders NSC-LSC1 promising as a compound for use in the field of chemotherapy of cancers.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:40:39 GMT 2023
by
admin
on
Sat Dec 16 04:40:39 GMT 2023
|
| Record UNII |
5DFG1UEB63
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID50163750
Created by
admin on Sat Dec 16 04:40:39 GMT 2023 , Edited by admin on Sat Dec 16 04:40:39 GMT 2023
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147557-12-8
Created by
admin on Sat Dec 16 04:40:39 GMT 2023 , Edited by admin on Sat Dec 16 04:40:39 GMT 2023
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5DFG1UEB63
Created by
admin on Sat Dec 16 04:40:39 GMT 2023 , Edited by admin on Sat Dec 16 04:40:39 GMT 2023
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11828953
Created by
admin on Sat Dec 16 04:40:39 GMT 2023 , Edited by admin on Sat Dec 16 04:40:39 GMT 2023
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PRIMARY |