Approval Year
| Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 10:33:11 GMT 2023
by
admin
on
Sat Dec 16 10:33:11 GMT 2023
|
| Protein Type | ENZYME |
| Protein Sub Type | CYTOCHROME P450 |
| Sequence Origin | HUMAN |
| Sequence Type | COMPLETE |
| Record UNII |
5DD3C4WV38
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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P15538
Created by
admin on Sat Dec 16 10:33:12 GMT 2023 , Edited by admin on Sat Dec 16 10:33:12 GMT 2023
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PRIMARY | |||
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5DD3C4WV38
Created by
admin on Sat Dec 16 10:33:12 GMT 2023 , Edited by admin on Sat Dec 16 10:33:12 GMT 2023
|
PRIMARY | |||
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457063-33-1
Created by
admin on Sat Dec 16 10:33:12 GMT 2023 , Edited by admin on Sat Dec 16 10:33:12 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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TISSUE EXPRESSION -> PARENT | |||
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SUBSTRATE -> METABOLIC ENZYME | |||
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INHIBITOR -> TARGET |
osilodrostat inhibited the activity of human CYP11B1 dose-dependently with IC50 values of 2.5 ± 0.1 nM (n = 4).
IC50
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| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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