Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C25H36O5S |
| Molecular Weight | 448.615 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12CC[C@](OC(=O)CCC)(C(=O)CS)[C@@]1(C)C[C@H](O)[C@@]3([H])[C@@]2([H])CCC4=CC(=O)CC[C@]34C
InChI
InChIKey=HOAKOHHSHOCDLI-TUFAYURCSA-N
InChI=1S/C25H36O5S/c1-4-5-21(29)30-25(20(28)14-31)11-9-18-17-7-6-15-12-16(26)8-10-23(15,2)22(17)19(27)13-24(18,25)3/h12,17-19,22,27,31H,4-11,13-14H2,1-3H3/t17-,18-,19-,22+,23-,24-,25-/m0/s1
| Molecular Formula | C25H36O5S |
| Molecular Weight | 448.615 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 7 / 7 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Butixocort, also known as tixocortol butyrate, is a synthetic locally acting thioester-linked corticosteroid glucocorticoid corticosteroid with potent anti-inflammatory activity developed by Jouveinal for treatment Allergic rhinitis and Asthma. Butixocort characterized by a large dissociation between it’s local and systemic effects; Butixocorts low or nonexistent glucocorticoid side effects are explained by its high systemic metabolic clearance. The dissociation between local activity and systemic side effects of Butixocorts has been found to be between 100 and 1000 times higher than those of beclomethasone dipropionate and budesonide.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:38:13 UTC 2023
by
admin
on
Fri Dec 15 16:38:13 UTC 2023
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| Record UNII |
5D0M4JI29K
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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Official Name | English | ||
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Systematic Name | English | ||
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Code | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C521
Created by
admin on Fri Dec 15 16:38:13 UTC 2023 , Edited by admin on Fri Dec 15 16:38:13 UTC 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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5D0M4JI29K
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Butixocort
Created by
admin on Fri Dec 15 16:38:13 UTC 2023 , Edited by admin on Fri Dec 15 16:38:13 UTC 2023
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CHEMBL2104187
Created by
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SUB06023MIG
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100000088631
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120815-74-9
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DTXSID701318350
Created by
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189904
Created by
admin on Fri Dec 15 16:38:13 UTC 2023 , Edited by admin on Fri Dec 15 16:38:13 UTC 2023
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6583
Created by
admin on Fri Dec 15 16:38:13 UTC 2023 , Edited by admin on Fri Dec 15 16:38:13 UTC 2023
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C83568
Created by
admin on Fri Dec 15 16:38:13 UTC 2023 , Edited by admin on Fri Dec 15 16:38:13 UTC 2023
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PRIMARY |
| Related Record | Type | Details | ||
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DERIVATIVE -> PARENT |
| Related Record | Type | Details | ||
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ACTIVE MOIETY |
