Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C11H16N2.2ClH |
| Molecular Weight | 249.18 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.C(N1CCNCC1)C2=CC=CC=C2
InChI
InChIKey=BBUJLUKPBBBXMU-UHFFFAOYSA-N
InChI=1S/C11H16N2.2ClH/c1-2-4-11(5-3-1)10-13-8-6-12-7-9-13;;/h1-5,12H,6-10H2;2*1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C11H16N2 |
| Molecular Weight | 176.2581 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action. | 2015-12 |
|
| Estrogenic effects and their action mechanism of the major active components of party pill drugs. | 2012-11-15 |
|
| Another bitter pill: a case of toxicity from DMAA party pills. | 2010-12-17 |
|
| Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors. | 2010-12 |
|
| Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine. | 2010-11 |
|
| A hybrid liquid chromatography-mass spectrometry strategy in a forensic laboratory for opioid, cocaine and amphetamine classes in human urine using a hybrid linear ion trap-triple quadrupole mass spectrometer. | 2010-10-29 |
|
| Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples. | 2010-10 |
|
| Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans. | 2010-09 |
|
| Randomised double-blind, placebo-controlled trial of the effects of the 'party pills' BZP/TFMPP alone and in combination with alcohol. | 2010-09 |
|
| Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate. | 2010-07-22 |
|
| Purchasing 'legal highs' on the Internet--is there consistency in what you get? | 2010-07 |
|
| Qualitative drug analysis of hair extracts by comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry. | 2010-06-25 |
|
| Head shop compound abuse amongst attendees of the Drug Treatment Centre Board. | 2010-05 |
|
| Hydride transfer reactions via ion-neutral complex: fragmentation of protonated N-benzylpiperidines and protonated N-benzylpiperazines in mass spectrometry. | 2010-05 |
|
| New benzofuran derivatives as an antioxidant agent. | 2010-03 |
|
| Multiorgan failure from 1-benzylpiperazine ingestion--legal high or lethal high? | 2010-03 |
|
| Differences in harm from legal BZP/TFMPP party pills between North Island and South Island users in New Zealand: a case of effective industry self-regulation? | 2010-01 |
|
| "They're legal so they're safe, right?" What did the legal status of BZP-party pills mean to young people in New Zealand? | 2010-01 |
|
| Legal highs toxicity--symptomatology and clinical diagnosis in case series. | 2010 |
|
| Determining the subjective and physiological effects of BZP on human females. | 2009-12 |
|
| In vivo interactions between BZP and TFMPP (party pill drugs). | 2009-09-25 |
|
| Metabolic interactions with piperazine-based 'party pill' drugs. | 2009-07 |
|
| 1-benzylpiperazine (BZP) abuse amongst attendees of the Drug Treatment Centre Board. | 2009-06 |
|
| Structure elucidation of a new designer benzylpiperazine: 4-bromo-2,5-dimethoxybenzylpiperazine. | 2009-05-30 |
|
| Party pills and drug-drug interactions. | 2009-04-24 |
|
| Pharmacokinetics of 'party pill' drug N-benzylpiperazine (BZP) in healthy human participants. | 2009-04-15 |
|
| Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine. | 2009-04 |
|
| A comparison of 1-benzylpiperazine and methamphetamine in their acute effects on anxiety-related behavior of hooded rats. | 2009-04 |
|
| Synthesis, optimization and structure-activity relationships of 3,5-disubstituted isoxazolines as new anti-tuberculosis agents. | 2009-02 |
|
| [Speed drugs]. | 2009 |
|
| Dissociative and sympathomimetic toxicity associated with recreational use of 1-(3-trifluoromethylphenyl) piperazine (TFMPP) and 1-benzylpiperzine (BZP). | 2008-12 |
|
| Patterns of benzylpiperazine/trifluoromethylphenylpiperazine party pill use and adverse effects in a population sample in New Zealand. | 2008-11 |
|
| Toxicity from the recreational use of 1-benzylpiperazine. | 2008-11 |
|
| Partying on? Life after BZP-based party pills. | 2008-10-03 |
|
| Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine. | 2008-08-04 |
|
| Detection of 1-benzylpiperazine and 1-(3-trifluoromethylphenyl)-piperazine in urine analysis specimens using GC-MS and LC-ESI-MS. | 2008-07-26 |
|
| 2-[2-(4-Benzyl-piperazin-1-ylcarbon-yl)eth-yl]-5,6-diphenyl-pyridazin-3(2H)-one. | 2008-05-10 |
|
| [1-benzylpiperazine (BZP) and 1-(3-trifluorométhylphényl)pipérazine (TFMPP): emergence of two agents which lead to misuse]. | 2008-03 |
|
| Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP. | 2008-03 |
|
| 1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine. | 2008-01-04 |
|
| N-benzylpiperazine has characteristics of a drug of abuse. | 2007-12 |
|
| Highs and lows: patterns of use, positive and negative effects of benzylpiperazine-containing party pills (BZP-party pills) amongst young people in New Zealand. | 2007-11-19 |
|
| MDMA-like behavioral effects of N-substituted piperazines in the mouse. | 2007-11 |
|
| Benzylpiperazine: a drug of abuse? | 2007-11 |
|
| Seizures in a night club. | 2007-07-21 |
|
| Chronic benzylpiperazine (BZP) exposure produces behavioral sensitization and cross-sensitization to methamphetamine (MA). | 2007-05-11 |
|
| Collapse, reported seizure--and an unexpected pill. | 2007-04-28 |
|
| Piperazine designer drugs of abuse. | 2007-04-28 |
|
| Party on? BZP party pills in New Zealand. | 2007-02-16 |
|
| Nitrofurans as novel anti-tuberculosis agents: identification, development and evaluation. | 2007 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 18:53:10 GMT 2025
by
admin
on
Tue Apr 01 18:53:10 GMT 2025
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| Record UNII |
5CFGYMNN06
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| Record Status |
Validated (UNII)
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| Record Version |
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